Compound Q&A

How is tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate (CAS: 365998-36-3) typically synthesized?

Answer

tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate
This compound can be synthesized via the condensation of tert-butyl isocyanate with (1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexanol. The reaction is typically catalyzed by a Lewis acid like zinc chloride, and the product has a high yield. The reaction is selective and efficient, with minimal side products.

About

English Name tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate
Molecular Formula C14H27N3O3
Molecular Weight 285.39 g/mol
SMILES CC(C)(C)OC(=O)NC1CC(CCC1N)C(=O)N(C)C
InChIKey JCHIBKSSZNWERE-GARJFASQSA-N
Last Updated: 2025-09-13 09:53

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