2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene

Basic Information

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CAS Number

36431-72-8

Molecular Formula

C13H22O

Molecular Weight

194.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

68-72 °C/3 mmHg

Refractive Index

n20/D 1.438(lit.)<br />n20/D 1.488

SMILES

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CC1CCC2(O1)C(=CCCC2(C)C)C

InChI

InChI=1S/C13H22O/c1-10-6-5-8-12(3,4)13(10)9-7-11(2)14-13/h6,11H,5,7-9H2,1-4H3

InChIKey

GYUZHTWCNKINPY-UHFFFAOYSA-N

LogP

3.690400000000003

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

264

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene
Spiroxide
Teaspirane
(+ -)-THEASPIRANE TECHN.
Theaspirane,mixture of cis and trans
Theaspirane
1-Oxaspiro4.5dec-6-ene,2,6,10,10-tetramethyl
dl-theaspirane
FEMA 3774
THEASPIRAN
THEASPIRANE MIXTURE OF CIS AND TR
theaspirane Is I
cis-Theaspirane
Theaspirane A
Theaspirane B
theaspirane, I
theaspirane, II
theaspirane Is II
(+/-)-Theaspirane
2,6,10,10-Tetramethyl-1-oxaspiro(4.5)dec-6-ene
AK115086
FEMA No. 3774
Theaspirane (Isomer 2)
Theaspirane (Iso

MDL Number

MFCD00085214

Customs Code

2932999099

FAQ

What are the physical and chemical properties of 2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene (CAS: 36431-72-8)?

2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene is a colorless liquid with a molecular weight of approximately 216.27 g/mol. It has a density of around 0.83 g/cm³ and a boiling point of about 90°C. The compound is slightly soluble in water but miscible with most organic solvents. It is mildly reactive, with limited reactivity under normal conditions but may undergo hydrolysis in the presence of water or strong acids.

How is 2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene (CAS: 36431-72-8) typically synthesized?

2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene is typically synthesized via a condensation reaction of 2,6,10,10-tetramethyl-1,10-undecanediol with acetic anhydride, catalyzed by a Lewis acid like aluminum trichloride. The yield is generally high, and the method is known for its good control over selectivity and purity.

What industries use 2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene (CAS: 36431-72-8)?

2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. Additionally, it is used in the polymer industry as a monomer for the production of specific polymers with unique properties. The compound also has applications in the sensor and semiconductor industries.

What precautions should be taken when handling 2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene (CAS: 36431-72-8)?

When handling 2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, immediately clean up the area using suitable absorbent materials and dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.