2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene(CAS: 36431-72-8)

2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene is a colorless liquid with a molecular weight of approximately 216.27 g/mol. It has a density of around 0.83 g/cm³ and a boiling point of about 90°C. The compound is slightly soluble in water but miscible with most organic solvents. It is mildly reactive, with limited reactivity under normal conditions but may undergo hydrolysis in the presence of water or strong acids.

2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene is typically synthesized via a condensation reaction of 2,6,10,10-tetramethyl-1,10-undecanediol with acetic anhydride, catalyzed by a Lewis acid like aluminum trichloride. The yield is generally high, and the method is known for its good control over selectivity and purity.

2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. Additionally, it is used in the polymer industry as a monomer for the production of specific polymers with unique properties. The compound also has applications in the sensor and semiconductor industries.

When handling 2,6,10,10-Tetramethyl-1-oxaspiro[4.5]dec-6-ene, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, immediately clean up the area using suitable absorbent materials and dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.