Ac-PHG-OMe | CAS No. 36060-84-1

Ac-PHG-OMe

Basic Information

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CAS Number

36060-84-1

Molecular Formula

C11H13NO3

Molecular Weight

207.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC(=O)NC(C1=CC=CC=C1)C(=O)OC

InChI

InChI=1S/C11H13NO3/c1-8(13)12-10(11(14)15-2)9-6-4-3-5-7-9/h3-7,10H,1-2H3,(H,12,13)/t10-/m0/s1

InChIKey

SAPRVTLHJXZROQ-JTQLQIEISA-N

LogP

1.42770

Complexity

234

Synonyms & References

English

AC-PHG-OME
36060-84-1
Methyl (2S)-acetamido(phenyl)acetate
Methyl (S)-2-acetamido-2-phenylacetate
SCHEMBL12880100
Benzeneacetic acid,a-(acetylamino)-,methyl ester,(as)-
DTXSID10427188
METHYL (2S)-2-ACETAMIDO-2-PHENYLACETATE
Acetyl-L-phenylglycine methyl ester
(S)-Methyl 2-acetamido-2-phenylacetate
Benzeneacetic acid, a-(acetylamino)-, methyl ester, (aS)-
Ac-Phg-OMe
methyl (2S)-2-acetamido-2-phenylacetate
(S)-Acetamide of phenylglycine methylester
(S)-N-acetyl-phenylglycine methyl ester
Benzeneaceticacid,a-(acetylamino)-,methyl ester,(S)
methyl (S)-N-acetylphenylglycinate
MethylL-2-acetamido-2-phenylacetate
N-Acetyl-L-phenylglycine methyl ester
N-acetyl-Phg-OMe

MDL Number

MFCD00237510

Customs Code

2924299090

FAQ

What are the physical and chemical properties of Ac-PHG-OMe (CAS: 36060-84-1)?

Ac-PHG-OMe (CAS: 36060-84-1) is a crystalline compound with a molecular weight of approximately 273.36 g/mol. It has a high solubility in organic solvents like dimethylformamide (DMF) and methanol. Chemically, it is relatively stable but can react with strong acids and bases. It is used in peptide synthesis and drug development due to its reactivity and functional groups.

How is Ac-PHG-OMe (CAS: 36060-84-1) typically synthesized?

Ac-PHG-OMe (CAS: 36060-84-1) is synthesized through the esterification of phenylglycine hydrochloride (PHG-HCl) with methanol in the presence of a base such as triethylamine. The reaction is highly selective and provides good yields, making it a common method for its synthesis in pharmaceutical laboratories.

What industries use Ac-PHG-OMe (CAS: 36060-84-1)?

Ac-PHG-OMe (CAS: 36060-84-1) is primarily used in the pharmaceutical industry for peptide synthesis and drug development. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for the production of certain organic electronic materials.

What precautions should be taken when handling Ac-PHG-OMe (CAS: 36060-84-1)?

When handling Ac-PHG-OMe (CAS: 36060-84-1), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or within a fume hood. Spills should be cleaned up carefully with appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures and disposal instructions.