Ac-PHG-OMe(CAS: 36060-84-1)

Ac-PHG-OMe (CAS: 36060-84-1) is a crystalline compound with a molecular weight of approximately 273.36 g/mol. It has a high solubility in organic solvents like dimethylformamide (DMF) and methanol. Chemically, it is relatively stable but can react with strong acids and bases. It is used in peptide synthesis and drug development due to its reactivity and functional groups.

Ac-PHG-OMe (CAS: 36060-84-1) is synthesized through the esterification of phenylglycine hydrochloride (PHG-HCl) with methanol in the presence of a base such as triethylamine. The reaction is highly selective and provides good yields, making it a common method for its synthesis in pharmaceutical laboratories.

Ac-PHG-OMe (CAS: 36060-84-1) is primarily used in the pharmaceutical industry for peptide synthesis and drug development. It is also utilized in the polymer industry for the modification of polymers and in the semiconductor industry for the production of certain organic electronic materials.

When handling Ac-PHG-OMe (CAS: 36060-84-1), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or within a fume hood. Spills should be cleaned up carefully with appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures and disposal instructions.