N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan

Basic Information

View in Editor

CAS Number

35737-15-6

Molecular Formula

C26H22N2O4

Molecular Weight

426.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

185.0 to 188.0 deg-C

Boiling Point

711.9°C at 760 mmHg

Flash Point

384.3℃

Refractive Index

-28.5 ° (C=1, DMF)

Specific Rotation

-29 º (c=1,DMF)

SMILES

View in Editor

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)O

InChI

InChI=1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/t24-/m0/s1

InChIKey

MGHMWKZOLAAOTD-DEOSSOPVSA-N

LogP

4.702300000000003

Topological Polar Surface Area

91.42 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

663

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AKOS012535969
Fmoc-L-Trp-OH
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)propanoic acid
HMS3030J08
BDBM50043810
L-Tryptophan, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
NS00057859
Fmoc-Trp-OH, >=97.0% (HPLC)
M03374
F0307
AM82281
(S)-2-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-3-(1H-INDOL-3-YL)PROPANOIC ACID
J-300269
Nalpha-FMOC-L-Tryptophan
N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-tryptophan (Fmoc-L-Trp-OH)
(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-tryptophan
9-FLUORENYLMETHOXYCARBONYL-L-TRYPTOPHAN
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
Fmoc-Trp-OH
AC-8601
EN300-81250
MFCD00037126
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]tryptophan #
NCGC00247299-01
A822965
CS-W011637
MLS001359854
(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)-propionic acid
CHEMBL292051
35737-15-6
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-indol-3-yl)propanoic acid

MDL Number

MFCD00037126

FAQ

What regulatory guidelines apply to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) must comply with the REACH regulations for chemical substances in the European Union, as well as the Toxic Substances Control Act (TSCA) and other relevant FDA and EPA regulations in the United States. It should also adhere to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) for proper hazard communication and labeling.

Are there alternatives to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) in synthesis?

In synthesis, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) can be replaced by similar compounds such as N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan or other related amino acids like N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine. Common alternative reagents include fluorenylmethyloxycarbonyl (Fmoc) derivatives, which are frequently used in solid-phase peptide synthesis.

What is the market or research trend for N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) is gaining interest in the pharmaceutical and biotechnology sectors for its potential in drug discovery. Research trends show increasing focus on its applications in peptide synthesis and medicinal chemistry. Market trends indicate a growing demand for this compound due to its unique chemical properties and potential in developing new drugs.

How should waste containing N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) be handled?

Waste containing N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) should be collected in proper containers and stored in a safe, secure location. It should be disposed of through professional waste disposal services that specialize in hazardous waste. Environmental protection precautions include ensuring no leakage and minimal exposure to the environment. Follow all local, state, and federal regulations for hazardous waste disposal.