Compound Q&A

Are there alternatives to N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) in synthesis?

Answer

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
In synthesis, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan (CAS: 35737-15-6) can be replaced by similar compounds such as N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tryptophan or other related amino acids like N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine. Common alternative reagents include fluorenylmethyloxycarbonyl (Fmoc) derivatives, which are frequently used in solid-phase peptide synthesis.

About

CAS No 35737-15-6
English Name N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
Molecular Formula C26H22N2O4
Molecular Weight 426.47 g/mol
SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)O
InChIKey MGHMWKZOLAAOTD-DEOSSOPVSA-N
Last Updated: 2025-09-06 09:47

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