piperidin-4-amine dihydrochloride

Basic Information

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CAS Number

35621-01-3

Molecular Formula

C5H14Cl2N2

Molecular Weight

173.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Yellow to Brown Solid

Melting Point

170.0℃~175.0℃

Boiling Point

158.9 °C at 760 mmHg

Flash Point

53.4 °C

SMILES

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C1CNCCC1N.Cl.Cl

InChI

InChI=1S/C5H12N2.2ClH/c6-5-1-3-7-4-2-5;;/h5,7H,1-4,6H2;2*1H

InChIKey

SGQDWDWJCYEUNC-UHFFFAOYSA-N

LogP

0.5407

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

piperidin-4-aminedihydrochloride
EN300-7353907
SY065921
CS-0069687
MFCD01570891
piperidin-4-yl-amine dihydrochloride
4-AMINOPIPERIDINE 2HCL
SCHEMBL1924289
AS-38361
A822908
piperidin-4-amine;dihydrochloride
AM85335
AKOS005259696
4-Aminopiperidine dihydrochloride
Piperidin-4-amine--hydrogen chloride (1/2)
SB41114
SGQDWDWJCYEUNC-UHFFFAOYSA-N
35621-01-3
DTXSID30641041
piperidin-4-amine dihydrochloride
4-Piperidinamine, dihydrochloride
FT-0657040
Piperidin-4-amine dihydrochloride
4-piperidinamine dihydrochloride
4-Piperidinamine,dihydrochloride (9CI)

MDL Number

MFCD01570891

Customs Code

2933399090

FAQ

What are the physical and chemical properties of piperidin-4-amine dihydrochloride (CAS: 35621-01-3)?

Piperidin-4-amine dihydrochloride is a crystalline compound with a molecular weight of approximately 219.74 g/mol. It is moderately soluble in water and slightly soluble in ethanol. The compound is known for its basic nature and can react with acids to form the dihydrochloride salt. It is stable under normal conditions but should be kept away from strong oxidizing agents.

How is piperidin-4-amine dihydrochloride (CAS: 35621-01-3) typically synthesized?

Piperidin-4-amine dihydrochloride is typically synthesized by the reaction of piperidine with hydrochloric acid. The process involves the substitution of a hydroxyl group with a chlorine atom followed by neutralization with sodium hydroxide to form the amine, which is then reacted with hydrochloric acid to form the dihydrochloride salt. The yield is generally around 85-90%, and the reaction is carried out under mild conditions.

What industries use piperidin-4-amine dihydrochloride (CAS: 35621-01-3)?

Piperidin-4-amine dihydrochloride is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of drugs. It is also used in the production of polymers and as a sensor material. Additionally, it has applications in the semiconductor industry for certain types of thin film applications.

What precautions should be taken when handling piperidin-4-amine dihydrochloride (CAS: 35621-01-3)?

When handling piperidin-4-amine dihydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of dust. In case of a spill, it should be immediately cleaned up using appropriate methods. Always refer to the safety data sheet (SDS) for specific handling and disposal procedures.