piperidin-4-amine dihydrochloride(CAS: 35621-01-3)

Piperidin-4-amine dihydrochloride is a crystalline compound with a molecular weight of approximately 219.74 g/mol. It is moderately soluble in water and slightly soluble in ethanol. The compound is known for its basic nature and can react with acids to form the dihydrochloride salt. It is stable under normal conditions but should be kept away from strong oxidizing agents.

Piperidin-4-amine dihydrochloride is typically synthesized by the reaction of piperidine with hydrochloric acid. The process involves the substitution of a hydroxyl group with a chlorine atom followed by neutralization with sodium hydroxide to form the amine, which is then reacted with hydrochloric acid to form the dihydrochloride salt. The yield is generally around 85-90%, and the reaction is carried out under mild conditions.

Piperidin-4-amine dihydrochloride is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of drugs. It is also used in the production of polymers and as a sensor material. Additionally, it has applications in the semiconductor industry for certain types of thin film applications.

When handling piperidin-4-amine dihydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of dust. In case of a spill, it should be immediately cleaned up using appropriate methods. Always refer to the safety data sheet (SDS) for specific handling and disposal procedures.