2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Basic Information

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CAS Number

35480-52-5

Molecular Formula

C11H8F6O4

Molecular Weight

318.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

121.0 to 125.0 deg-C

Boiling Point

354.1℃ at 760 mmHg

Density

1.474

Flash Point

168℃

Refractive Index

1.438

SMILES

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C1=CC(=C(C=C1OCC(F)(F)F)C(=O)O)OCC(F)(F)F

InChI

InChI=1S/C11H8F6O4/c12-10(13,14)4-20-6-1-2-8(7(3-6)9(18)19)21-5-11(15,16)17/h1-3H,4-5H2,(H,18,19)

InChIKey

YPGYLCZBZKRYQJ-UHFFFAOYSA-N

LogP

3.2670000000000012

Topological Polar Surface Area

55.760000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

354

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

35480-52-5
2,5-bis(2,2,2-trifluoroethoxy)benzoic acid, AldrichCPR
2,5-bis(2,2,2-trifluorethoxy)benzoic acid
ID4JP01L3W
MFCD00221424
EN300-76845
EC 609-132-9
AC-3902
B3227
UNII-ID4JP01L3W
2,5-bis (2,2,2-trifluoroethoxy)benzoic acid
PS-7060
A19961
2,5-Bis(2,2,2-trifluoroethoxy)benzoicAcid
BENZOIC ACID, 2,5-BIS(2,2,2-TRIFLUOROETHOXY)-
2,5-bis(2,2,2-trifluoroethoxy)benzoic Acid
2,5-Bis(2,2,2-trifluoroethoxy)benzoicAcid-d3
Flecainide Acetate Imp. D (EP); 2,5-Bis(2,2,2-trifluoroethoxy)benzoic Acid; Flecainide Acetate Impurity D; Flecainide Impurity D
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
2,5-bis(trifluoroethoxy)benzoic acid
Z1190330980
SCHEMBL978291
NS00003212
FLECAINIDE ACID [USP IMPURITY]
2,5-Di(2,2,2-trifluoroethoxy)benzoic acid
DTXSID50371111
FLECAINIDE ACETATE IMPURITY D [EP IMPURITY]
Q-100990
AKOS015852999
PD065532
Flecainide IMpurity D

MDL Number

MFCD00221424

Customs Code

2918990090

FAQ

What is 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5)?

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5) is an organic compound with the molecular formula C14H10F9O4. It features a benzene ring substituted with two 2,2,2-trifluoroethoxy groups and a carboxylic acid functional group. This compound is known for its high reactivity due to fluorine atoms and is typically a white solid with low solubility in water. Its structure makes it valuable in chemical synthesis and specialized applications requiring fluorinated derivatives.

What are the main uses of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5)?

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5) is primarily used in pharmaceutical research as a precursor for drug development. It also finds applications in industrial processes, including polymer synthesis and coating materials, due to its fluorinated properties. Additionally, it is utilized in agrochemicals and as an intermediate in the production of specialized chemicals, leveraging its stability and reactivity in controlled environments.

Is 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5) safe?

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5) requires careful handling due to potential toxicity from fluorine compounds. It is advisable to use protective equipment like gloves and goggles, ensure proper ventilation, and avoid skin or inhalation contact. Safety standards emphasize adherence to chemical handling protocols, and it is not intended for use in food or consumer products. Always follow OSHA guidelines for safe exposure and disposal.

How should 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5) be stored?

Store 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS: 35480-52-5) in a cool, dry place with low humidity, away from direct light. Use airtight containers, preferably made of glass or HDPE, to prevent moisture absorption and contamination. Maintain storage temperatures below 25°C and avoid contact with incompatible substances. Ensure the container is labeled properly and kept in a secure chemical storage area for stability and safety.