2-(3,4-Dimethoxyphenyl)-N-methylethanamine

Basic Information

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CAS Number

3490-06-0

Molecular Formula

C11H17NO2

Molecular Weight

195.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

100°C/0.1mmHg

Flash Point

>110 ºC

Refractive Index

1.533

SMILES

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CNCCC1=CC(=C(C=C1)OC)OC

InChI

InChI=1S/C11H17NO2/c1-12-7-6-9-4-5-10(13-2)11(8-9)14-3/h4-5,8,12H,6-7H2,1-3H3

InChIKey

HNJWKRMESUMDQE-UHFFFAOYSA-N

LogP

1.4657

Topological Polar Surface Area

30.49 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

152

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

3490-06-0
N-methyl-3,4-dimethoxybenzeneethanamine
MFCD00067696
AKOS000271141
W-106700
NCGC00247003-01
VERAPAMIL HYDROCHLORIDE IMPURITY B [EP IMPURITY]
N-methyl-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-amine
D2104
3,4-dimethoxyphenylethyl-N-methylamine
SMR000112502
N-Methyl-2-(3,4-dimethoxyphenyl)-ethylamine
NSC-187772
NS00003786
N-methyl-N[2-(3,4-dimethoxy-phenyl)-ethyl]-amine
N-(3,4-dimethoxy-phenylethyl)-N-methyl-amine
UNII-5H5ZH95EHG
N-(3,4-dimethoxyphenylethyl)-N-methylamine
N-Methylhomoveratrylamine, 97%
CHEMBL1404381
EC 222-483-9
2-(3,4-Dimethoxyphenyl)-N-methyl-d3-ethylamine
FD10469
N-methyl-(2-(3,4-dimethoxyphenyl)ethyl)amine
2-(3,4-DIMETHOXYPHENYL)-N-METHYLETHAN-1-AMINE
AS-48860
Q27262167
N-(3,4-dimethoxy-phenylethyl)-N-methylamine
2-(3 pound not4-Dimethoxyphenyl)-N-methylethylamine
5H5ZH95EHG
N-[2-(3,4-dimethoxyphenyl)-ethyl]-N-methylamine

MDL Number

MFCD00067696

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 2-(3,4-Dimethoxyphenyl)-N-methylethanamine (CAS: 3490-06-0)?

2-(3,4-Dimethoxyphenyl)-N-methylethanamine has a crystalline form. Its molecular weight is approximately 244.25 g/mol. This compound is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. It is moderately reactive towards acidic and basic conditions. It can undergo substitution and alkylation reactions commonly observed in amine derivatives.

How is 2-(3,4-Dimethoxyphenyl)-N-methylethanamine (CAS: 3490-06-0) typically synthesized?

2-(3,4-Dimethoxyphenyl)-N-methylethanamine is typically synthesized via a multistep process involving the alkylation of 3,4-dimethoxyphenol with methylamine. The key steps include the formation of the phenol intermediate, subsequent alkylation with methylamine, and purification. Commonly used solvents include toluene or dimethylformamide (DMF), and the reaction is catalyzed by a Lewis acid like aluminum chloride (AlCl₃). The overall yield is around 70-75%.

What industries use 2-(3,4-Dimethoxyphenyl)-N-methylethanamine (CAS: 3490-06-0)?

2-(3,4-Dimethoxyphenyl)-N-methylethanamine is used in various industries, particularly in pharmaceuticals and fine chemicals. It serves as a precursor for the synthesis of active pharmaceutical ingredients (APIs) and is also utilized in the production of certain dyes and pigments. Due to its functional groups, it is also employed in polymer synthesis and as a sensing agent in analytical chemistry.

What precautions should be taken when handling 2-(3,4-Dimethoxyphenyl)-N-methylethanamine (CAS: 3490-06-0)?

When handling 2-(3,4-Dimethoxyphenyl)-N-methylethanamine, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with caution, using absorbent materials and disposing of the waste according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.