Compound Q&A

How is 2-(3,4-Dimethoxyphenyl)-N-methylethanamine (CAS: 3490-06-0) typically synthesized?

Answer

2-(3,4-Dimethoxyphenyl)-N-methylethanamine
2-(3,4-Dimethoxyphenyl)-N-methylethanamine is typically synthesized via a multistep process involving the alkylation of 3,4-dimethoxyphenol with methylamine. The key steps include the formation of the phenol intermediate, subsequent alkylation with methylamine, and purification. Commonly used solvents include toluene or dimethylformamide (DMF), and the reaction is catalyzed by a Lewis acid like aluminum chloride (AlCl₃). The overall yield is around 70-75%.

About

CAS No 3490-06-0
English Name 2-(3,4-Dimethoxyphenyl)-N-methylethanamine
Molecular Formula C11H17NO2
Molecular Weight 195.26 g/mol
SMILES CNCCC1=CC(=C(C=C1)OC)OC
InChIKey HNJWKRMESUMDQE-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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