8-Chloroisoquinoline

Basic Information

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CAS Number

34784-07-1

Molecular Formula

C9H6ClN

Molecular Weight

163.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

289.5°C at 760 mmHg

Density

1.27

Flash Point

156.4°C

Refractive Index

1.652

SMILES

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C1=CC2=C(C=NC=C2)C(=C1)Cl

InChI

InChI=1S/C9H6ClN/c10-9-3-1-2-7-4-5-11-6-8(7)9/h1-6H

InChIKey

OXAMVYYZTULFIB-UHFFFAOYSA-N

LogP

2.8882000000000003

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

138

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

J-519426
SCHEMBL619607
MFCD07644622
8-Chloroisoquinoline, AldrichCPR
InChI=1/C9H6ClN/c10-9-3-1-2-7-4-5-11-6-8(7)9/h1-6
SB36756
AKOS005255311
A6105
8-Chloro-isoquinoline
CS-W022565
Z1201624136
PS-6079
AMY17939
DTXSID70348825
EN300-215652
34784-07-1
SY019969
OXAMVYYZTULFIB-UHFFFAOYSA-N
isoquinoline, 8-chloro-
J-019751
FT-0659536
8-chloroisoquinoline
8-Chloroisoquinoline
PubChem6216
TRA0089653
AB0038047
Y5393
784C071

MDL Number

MFCD07644622

Customs Code

2933499090

FAQ

What regulatory guidelines apply to 8-Chloroisoquinoline (CAS: 34784-07-1)?

8-Chloroisoquinoline (CAS: 34784-07-1) falls under the classification of hazardous chemicals under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). It is subject to REACH regulations in the European Union, requiring manufacturers and importers to register substances with the European Chemicals Agency. In the United States, the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) have specific regulations for the handling, storage, and disposal of this compound. Compliance with these guidelines is essential for safety and legal compliance.

Are there alternatives to 8-Chloroisoquinoline (CAS: 34784-07-1) in synthesis?

While 8-Chloroisoquinoline (CAS: 34784-07-1) is a useful intermediate in organic synthesis, alternatives include other isoquinolines such as 8-aminooxazoloisoquinoline and 8-aminoperhydroisoquinoline. Common reagents for its synthesis include chlorinating agents like thionyl chloride or phosphorus oxychloride. These alternatives can offer similar functional group transformations but with varying degrees of reactivity and selectivity.

What is the market or research trend for 8-Chloroisoquinoline (CAS: 34784-07-1)?

The market for 8-Chloroisoquinoline (CAS: 34784-07-1) is driven by its applications in pharmaceuticals, agrochemicals, and research. Recent trends show an increasing demand for this compound due to its role as an intermediate in the synthesis of various bioactive molecules. Research is also exploring its use in new drug development and as a starting material for organic synthesis. The market is expected to grow with ongoing innovation in these fields.

How should waste containing 8-Chloroisoquinoline (CAS: 34784-07-1) be handled?

Waste containing 8-Chloroisoquinoline (CAS: 34784-07-1) should be collected in appropriate containers, ensuring they are sealed to prevent spillage. The waste should then be safely transported to a professional waste disposal facility. Incineration is a common method of disposal, but it must be conducted in compliance with local environmental regulations. For environmental protection, it is crucial to follow safety guidelines and ensure minimal environmental impact during the disposal process.