2,2'-Bipyrimidine

Basic Information

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CAS Number

34671-83-5

Molecular Formula

C8H6N4

Molecular Weight

158.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

113°C

Boiling Point

395.4°C at 760 mmHg

Flash Point

197.0±16.1 °C

Solubility

Soluble in methanol.

Refractive Index

1.592

SMILES

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C1=CN=C(N=C1)C2=NC=CC=N2

InChI

InChI=1S/C8H6N4/c1-3-9-7(10-4-1)8-11-5-2-6-12-8/h1-6H

InChIKey

HKOAFLAGUQUJQG-UHFFFAOYSA-N

LogP

0.9335999999999998

Topological Polar Surface Area

51.56 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

111

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2,2'-Dipyrimidyl
2,2'-Bipyrimidine
2,2'-DIPYRIMIDINE
AM85737
2,2'-Bipyrimidine, 95%
2,2'-Bipyrimidyl
UNII-Y67VU82SCE
DS-13604
Bipyrimidine
2-pyrimidin-2-ylpyrimidine
HKOAFLAGUQUJQG-UHFFFAOYSA-N
Y67VU82SCE
2-(pyrimidin-2-yl)pyrimidine
bpym
YSWG509
SY039350
AKOS015840944
2,2`-Bipyrimidine
EN300-112116
CS-W008340
J-400158
EINECS 252-137-2
2,2'-Bipyrimidinyl
SCHEMBL171853
34671-83-5
B2496
AC-22790
MFCD00014600
NS00029706
2,2 inverted exclamation mark -Bipyrimidine
DTXSID50188226

MDL Number

MFCD00014600

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 2,2'-Bipyrimidine (CAS: 34671-83-5)?

2,2'-Bipyrimidine is a crystalline solid with a high melting point. Its molecular weight is approximately 168.13 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. Chemically, it is highly stable but can react with bases to form complexes. It is a versatile molecule used in various chemical reactions due to its planar structure and strong π-conjugation.

How is 2,2'-Bipyrimidine (CAS: 34671-83-5) typically synthesized?

2,2'-Bipyrimidine is commonly synthesized by the condensation of two molecules of 2-bromopyrimidine using sodium hydride as a base. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is typically around 75-80%, and the method is known for its good selectivity.

What industries use 2,2'-Bipyrimidine (CAS: 34671-83-5)?

2,2'-Bipyrimidine is widely used in pharmaceuticals for its role as a building block in drug synthesis. It is also utilized in the development of polymers, particularly in conducting polymers, and in the fabrication of sensors due to its planar structure and strong electronic properties. Additionally, it is employed in semiconductor applications for its ability to form stable complexes.

What precautions should be taken when handling 2,2'-Bipyrimidine (CAS: 34671-83-5)?

When handling 2,2'-Bipyrimidine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be performed in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately with appropriate absorbents. For proper handling and safety information, always refer to the Material Safety Data Sheet (MSDS/SDS).