2,2'-Bipyrimidine(CAS: 34671-83-5)

2,2'-Bipyrimidine is a crystalline solid with a high melting point. Its molecular weight is approximately 168.13 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. Chemically, it is highly stable but can react with bases to form complexes. It is a versatile molecule used in various chemical reactions due to its planar structure and strong π-conjugation.

2,2'-Bipyrimidine is commonly synthesized by the condensation of two molecules of 2-bromopyrimidine using sodium hydride as a base. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is typically around 75-80%, and the method is known for its good selectivity.

2,2'-Bipyrimidine is widely used in pharmaceuticals for its role as a building block in drug synthesis. It is also utilized in the development of polymers, particularly in conducting polymers, and in the fabrication of sensors due to its planar structure and strong electronic properties. Additionally, it is employed in semiconductor applications for its ability to form stable complexes.

When handling 2,2'-Bipyrimidine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be performed in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately with appropriate absorbents. For proper handling and safety information, always refer to the Material Safety Data Sheet (MSDS/SDS).