(1R,3R)-3-Aminocyclohexanecarboxylic acid | CAS No. 34583-99-8

(1R,3R)-3-Aminocyclohexanecarboxylic acid

Basic Information

CAS Number

34583-99-8

Molecular Formula

C7H13NO2

Molecular Weight

143.19 g/mol

AD

Basic Physical Properties

C1CC(CC(C1)N)C(=O)O

InChI

InChI=1S/C7H13NO2/c8-6-3-1-2-5(4-6)7(9)10/h5-6H,1-4,8H2,(H,9,10)/t5-,6-/m1/s1

InChIKey

CKTUXQBZPWBFDX-PHDIDXHHSA-N

LogP

0.5884999999999998

Topological Polar Surface Area

63.32000000000001 Ų

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

136

Synonyms & References

English

  • trans-3-Aminocyclohexanecarboxylic acid
  • EN300-358884
  • trans-3-Aminocyclohexanecarboxylicacid
  • 933445-51-3
  • EN300-171990
  • P11799
  • (1R,3R)-3-aminocyclohexane-1-carboxylic acid
  • 34583-99-8
  • AS-51054
  • Z2309783249
  • (1R,3R)-3-Aminocyclohexanecarboxylic acid
  • rac-(1R,3R)-3-aminocyclohexane-1-carboxylic acid
  • AKOS006338133
  • Cyclohexanecarboxylic acid,3-amino-,trans-
  • SCHEMBL2381818
  • CS-0055004
  • (1R,3R)-3-aminocyclohexanecarboxylic acid
  • Cyclohexanecarboxylic acid, 3-amino-, trans-
  • 1,3-trans-Aminocyclohexanecarboxylicacid
  • trans-3-Aminocyclohexane-1-carboxylic acid
  • trans-3-aminocyclohexane-1-carboxylic acid

MDL Number

MFCD15478849

FAQ

What are the physical and chemical properties of (1R,3R)-3-Aminocyclohexanecarboxylic acid (CAS: 34583-99-8)?

(1R,3R)-3-Aminocyclohexanecarboxylic acid is a white crystalline solid with a molecular weight of approximately 149.18 g/mol. It has a pKa of about 4.5 and is slightly soluble in water but more soluble in organic solvents. It is known for its reactivity in amide and ester formation reactions.

How is (1R,3R)-3-Aminocyclohexanecarboxylic acid (CAS: 34583-99-8) typically synthesized?

(1R,3R)-3-Aminocyclohexanecarboxylic acid can be synthesized via the Kolbe-Schmitt reaction, where cyclohexanecarboxylic acid is treated with sodium amide in liquid ammonia. This method provides high yield and excellent selectivity.

What industries use (1R,3R)-3-Aminocyclohexanecarboxylic acid (CAS: 34583-99-8)?

(1R,3R)-3-Aminocyclohexanecarboxylic acid is used in the pharmaceutical industry for the synthesis of drugs, and in the polymer industry for the production of biodegradable polymers. It also finds applications in the development of sensors and as a raw material in semiconductor manufacturing.

What precautions should be taken when handling (1R,3R)-3-Aminocyclohexanecarboxylic acid (CAS: 34583-99-8)?

When handling (1R,3R)-3-Aminocyclohexanecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately, and the material safety data sheet (MSDS) should be consulted for detailed emergency procedures.

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