(1R,3R)-3-Aminocyclohexanecarboxylic acid(CAS: 34583-99-8)

(1R,3R)-3-Aminocyclohexanecarboxylic acid is a white crystalline solid with a molecular weight of approximately 149.18 g/mol. It has a pKa of about 4.5 and is slightly soluble in water but more soluble in organic solvents. It is known for its reactivity in amide and ester formation reactions.

(1R,3R)-3-Aminocyclohexanecarboxylic acid can be synthesized via the Kolbe-Schmitt reaction, where cyclohexanecarboxylic acid is treated with sodium amide in liquid ammonia. This method provides high yield and excellent selectivity.

(1R,3R)-3-Aminocyclohexanecarboxylic acid is used in the pharmaceutical industry for the synthesis of drugs, and in the polymer industry for the production of biodegradable polymers. It also finds applications in the development of sensors and as a raw material in semiconductor manufacturing.

When handling (1R,3R)-3-Aminocyclohexanecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately, and the material safety data sheet (MSDS) should be consulted for detailed emergency procedures.