5-Methyl-3-pyridinamine

Basic Information

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CAS Number

3430-19-1

Molecular Formula

C6H8N2

Molecular Weight

108.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

63.0 to 67.0 deg-C

Boiling Point

155°C/21mmHg

Density

1.068

Flash Point

135.6℃

Refractive Index

1.574

SMILES

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CC1=CC(=CN=C1)N

InChI

InChI=1S/C6H8N2/c1-5-2-6(7)4-8-3-5/h2-4H,7H2,1H3

InChIKey

JXUWZXFVCBODAN-UHFFFAOYSA-N

LogP

0.9722200000000001

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

72.9

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class TOXIC Class TOXIC

Synonyms & References

English

AB17573
5-methyl-3-pyridylamine hydrochloride salt
EN300-87442
AC-24961
FT-0648087
3-Amino-5-methylpyridine, 97%
A6037
SCHEMBL114938
DTXSID90376549
FT-0658820
DS-0479
5-Amino-3-picoline
5-Methyl-pyridin-3-ylamine
J-019548
J-517823
JXUWZXFVCBODAN-UHFFFAOYSA-N
SY016906
5-methylpyridine-3-amine
3-Amino-5-methylpyridine (3-Amino-5-picoline)
3-amino-5-methyl pyridine
MFCD04112508
BCP22174
3430-19-1
PS-9290
CS-W003151
AKOS005257653
5-methyl-3-pyridineamine
5-methylpyridin-3-amine
5-Methyl-3-pyridinylamine
3-amino-5-picoline
3-PYRIDINAMINE, 5-METHYL-

MDL Number

MFCD04112508

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Methyl-3-pyridinamine (CAS: 3430-19-1)?

5-Methyl-3-pyridinamine is a crystalline solid with a molecular weight of approximately 114.13 g/mol. It has a pKa of about 5.5 and is moderately soluble in water. This compound is highly reactive towards acidic and basic conditions. It is used in organic synthesis and as an intermediate in the production of pharmaceuticals and other chemicals.

How is 5-Methyl-3-pyridinamine (CAS: 3430-19-1) typically synthesized?

5-Methyl-3-pyridinamine can be synthesized through a multi-step process involving the reaction of 3-pyridone with methylamine. This process typically uses a catalyst and proceeds with good selectivity. The overall yield is around 70%, and the method is widely used in academic and industrial settings for the production of this compound.

What industries use 5-Methyl-3-pyridinamine (CAS: 3430-19-1)?

5-Methyl-3-pyridinamine is primarily used in the pharmaceuticals industry as an intermediate in the synthesis of various drugs. It is also employed in the production of certain sensors and semiconductors due to its unique chemical properties. Its versatility makes it a valuable compound in both academic and industrial research.

What precautions should be taken when handling 5-Methyl-3-pyridinamine (CAS: 3430-19-1)?

When handling 5-Methyl-3-pyridinamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up promptly with appropriate absorbents, and proper disposal methods should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.