5-Methyl-3-pyridinamine(CAS: 3430-19-1)

5-Methyl-3-pyridinamine is a crystalline solid with a molecular weight of approximately 114.13 g/mol. It has a pKa of about 5.5 and is moderately soluble in water. This compound is highly reactive towards acidic and basic conditions. It is used in organic synthesis and as an intermediate in the production of pharmaceuticals and other chemicals.

5-Methyl-3-pyridinamine can be synthesized through a multi-step process involving the reaction of 3-pyridone with methylamine. This process typically uses a catalyst and proceeds with good selectivity. The overall yield is around 70%, and the method is widely used in academic and industrial settings for the production of this compound.

5-Methyl-3-pyridinamine is primarily used in the pharmaceuticals industry as an intermediate in the synthesis of various drugs. It is also employed in the production of certain sensors and semiconductors due to its unique chemical properties. Its versatility makes it a valuable compound in both academic and industrial research.

When handling 5-Methyl-3-pyridinamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up promptly with appropriate absorbents, and proper disposal methods should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.