2-chloro-N-[5-(2-chloroacetamido)pentyl]acetamide | CAS No. 33619-33-9

2-chloro-N-[5-(2-chloroacetamido)pentyl]acetamide

Basic Information

CAS Number

33619-33-9

Molecular Formula

C9H16Cl2N2O2

Molecular Weight

255.14 g/mol

AD

Basic Physical Properties

C(CCNC(=O)CCl)CCNC(=O)CCl

InChI

InChI=1S/C9H16Cl2N2O2/c10-6-8(14)12-4-2-1-3-5-13-9(15)7-11/h1-7H2,(H,12,14)(H,13,15)

InChIKey

YHXXCHVUPKCXGH-UHFFFAOYSA-N

LogP

0.8666999999999998

Topological Polar Surface Area

58.2 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

181

Synonyms & References

English

  • CS-0236317
  • NSC58836
  • BS-52519
  • DTXSID30955251
  • NSC-58836
  • N,N'-(Pentane-1,5-diyl)bis(2-chloroethanimidic acid)
  • N,N'-(Pentane-1,5-diyl)bis(2-chloroacetamide)
  • EN300-1703001
  • 2-chloro-N-{5-[(chloroacetyl)amino]pentyl}acetamide
  • E73804
  • 2-chloro-N-[5-[(2-chloroacetyl)amino]pentyl]acetamide
  • 33619-33-9
  • 2-CHLORO-N-[5-(2-CHLOROACETAMIDO)PENTYL]ACETAMIDE
  • AKOS024343883
  • 1,1'-naphthalene-1,5-diyl-bis-pyrrole-2-carboxylic acid
  • 1,5-Bis-(2'-carboxypyrrol-1'yl)naphthalin
  • 1,5-Bis-(2-chlor-acetylamino)-pentan
  • 1,5-bis-(2-chloro-acetylamino)-pentane
  • 2-chloro-N-[5-(2-chloro-acetylamino)-pentyl]acetamide
  • AC1L7COH
  • N,N'-Pentamethylendi-(chloracetamid)
  • NSC209519
  • Acetamide,N,N'-1,5-pentanediylbis[2-chloro-
  • 2-chloro-N-5-(2-chloroacetamido)pentylacetamide

MDL Number

MFCD00455513

FAQ

What are the physical and chemical properties of 2-chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9)?

2-Chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9) is a crystalline solid with a molecular weight of approximately 322.06 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dimethylformamide. The compound is known for its reactivity, particularly towards nucleophiles, and it can undergo hydrolysis under basic conditions. It is also susceptible to degradation upon exposure to heat and light.

How is 2-chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9) typically synthesized?

2-Chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9) is typically synthesized via the condensation of 2-chloropentanediamine with acetyl chloride. The reaction proceeds in the presence of a Lewis acid catalyst such as aluminum chloride. The yield can be maximized by controlling the reaction temperature and ensuring a stoichiometric ratio of reactants. The product is then purified by recrystallization from ethanol.

What industries use 2-chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9)?

2-Chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9) finds applications in the pharmaceutical industry for its use as a precursor in the synthesis of bioactive compounds. It is also utilized in the polymer industry as a functional monomer for the preparation of advanced polymers with specific properties. Additionally, it has found uses in the development of sensors and as a component in certain semiconductors.

What precautions should be taken when handling 2-chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9)?

When handling 2-chloro-N-[5-(2-chloroacetamido)pentyl]acetamide (CAS: 33619-33-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood due to its potential to release toxic fumes. Spills should be cleaned up with care, using appropriate absorbents, and the area should be well-ventilated. SDS (Safety Data Sheet) should be consulted for detailed information on proper handling and emergency procedures.

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