trans-4-methylcyclohexanamine;hydrochloride

Basic Information

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CAS Number

33483-65-7

Molecular Formula

C7H16ClN

Molecular Weight

149.67 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

261-263°C

Boiling Point

195.9°Cat760mmHg

Flash Point

72.3°C

SMILES

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CC1CCC(CC1)N.Cl

InChI

InChI=1S/C7H15N.ClH/c1-6-2-4-7(8)5-3-6;/h6-7H,2-5,8H2,1H3;1H/t6-,7-;

InChIKey

GIRKJSRZELQHDX-MEZFUOHNSA-N

LogP

1.9455999999999998

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

62.8

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(1S,4S)-4-METHYLCYCLOHEXAN-1-AMINE HYDROCHLORIDE
4-MethylcyclohexylamineHydrochloride
M0957
cis-4-methylcyclohexan-1-amine hydrochloride
Cyclohexanamine, 4-methyl-, hydrochloride (1:1), cis-
A5966
trans-4-methylcyclohexylamine hcl
cis-4-Methylcyclohexylamine Hydrochloride
33483-66-8
(TRANS)-4-METHYL CYCLOHEXYL AMINE HYDROCHLORIDE
MFCD09991703
FT-0656976
EN300-72659
EN300-7386067
AKOS015894277
trans-4-Methylcyclohexylamine, HCl
100959-19-1
(1s,4s)-4-methylcyclohexanamine hydrochloride
CS-0170852
FT-0639102
(Trans-4-methylcyclohexylaminehydrochloride)
Trans-4-methyl cyclohexyl amine Hydrochloride
D91414
(1r,4r)-4-methylcyclohexanamine hydrochloride
4-Methylcyclohexanamine HCl
SCHEMBL1076485
Cyclohexanamine, 4-methyl-, hydrochloride (1:1)
Cis-4-methyl-cyclohexylamine, HCl
SB36662
SY235531
cis-4-methylcyclohexanamine hydrochloride

MDL Number

MFCD07368256

Customs Code

2921300090

FAQ

What are the physical and chemical properties of trans-4-methylcyclohexanamine hydrochloride (CAS: 33483-65-7)?

Trans-4-methylcyclohexanamine hydrochloride is a crystalline solid with a molecular weight of approximately 171.68 g/mol. It has a solubility of about 7 g/100 mL in water and is sparingly soluble in ethanol. Chemically, it is mildly basic and can react with acids to form salts. It is stable under normal conditions but should be stored in a dry environment to prevent hydrolysis.

How is trans-4-methylcyclohexanamine hydrochloride (CAS: 33483-65-7) typically synthesized?

Trans-4-methylcyclohexanamine hydrochloride is typically synthesized by first preparing trans-4-methylcyclohexanamine from trans-4-methylcyclohexanol using hydrochloric acid. The reaction involves the amination of the alcohol to form the amine, followed by the formation of the hydrochloride salt. Commonly used conditions include refluxing the mixture in a water bath to achieve high selectivity and yield.

What industries use trans-4-methylcyclohexanamine hydrochloride (CAS: 33483-65-7)?

Trans-4-methylcyclohexanamine hydrochloride is used in the pharmaceutical industry as a precursor in drug synthesis. It is also utilized in the polymer industry for the manufacturing of certain types of plastics and adhesives. Additionally, it finds applications in the sensor industry for specific chemical sensing applications and in the semiconductor industry for various fabrication processes.

What precautions should be taken when handling trans-4-methylcyclohexanamine hydrochloride (CAS: 33483-65-7)?

When handling trans-4-methylcyclohexanamine hydrochloride, appropriate personal protective equipment (PPE) should be used, including gloves, goggles, and a laboratory coat. Work should be conducted in a fume hood to minimize exposure. In case of a spill, it should be cleaned up using absorbent materials and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for detailed handling and disposal information.