D-Leucine | CAS No. 328-38-1

D-Leucine

Basic Information

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CAS Number

328-38-1

Molecular Formula

C6H13NO2

Molecular Weight

131.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Solid

Melting Point

>300 °C

Boiling Point

225.8°C at 760 mmHg

Water Solubility

24 g/L (25 ºC)

Flash Point

90.3 °C

Refractive Index

-15 ° (C=4, 6mol/L HCl)

Specific Rotation

-15.45 º (c=4, 6N HCl)

SMILES

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CC(C)CC(C(=O)O)N

InChI

InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1

InChIKey

ROHFNLRQFUQHCH-RXMQYKEDSA-N

LogP

0.44439999999999996

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

101

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

UNII-965COD96YA
(R)-(-)-Leucine
(2R)-2-azaniumyl-4-methylpentanoate
CS-D1369
AS-12286
Leucine,d
Q16081973
D-Leucine, ReagentPlus(R), 99%
MFCD00063088
D-2-Amino-4-methylvaleric acid
NCGC00163335-03
NCGC00163335-02
CHEBI:28225
D-Leucine, Vetec(TM) reagent grade, 97%
(R)-4-METHYL-2-AMINOPENTANOIC ACID
Leucine, D-
AM81870
DLE
(R)-Leucine
(R)-2-Amino-4-methylvaleric acid
AC-8658
EINECS 206-327-7
AI3-52422
H-D-Leu-OH
NCGC00163335-01
BCP30475
HY-Y0378
D-Leucin
DTXSID6046347
Tox21_112049
C01570

MDL Number

MFCD00063088

Customs Code

29224995

FAQ

What is D-Leucine (CAS: 328-38-1)?

D-Leucine is a synthetic amino acid, specifically the D-enantiomer of leucine, which is a branched-chain amino acid essential for protein synthesis. Its chemical formula is C6H13NO2. It is commonly used in biochemical research and has similar chemical properties to L-Leucine, though it exhibits different biological activities due to its stereochemistry.

What are the main uses of D-Leucine (CAS: 328-38-1)?

D-Leucine is primarily used in pharmaceutical research, particularly in the development of drugs and as a chiral building block. It also finds applications in the food industry as a flavor enhancer and in biochemical studies to investigate enzyme specificity and stereochemical effects. Additionally, it is utilized in the synthesis of various organic compounds and as a component in some dietary supplements.

Is D-Leucine (CAS: 328-38-1) safe?

D-Leucine is generally considered safe when handled properly, but it should be used with caution as it may have different biological effects compared to its L-enantiomer. Safety data indicates that it is not classified as toxic, but appropriate protective measures such as gloves and ventilation are recommended during handling to ensure safe exposure and minimize risk.

How should D-Leucine (CAS: 328-38-1) be stored?

D-Leucine should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is typically kept in a sealed container to prevent moisture absorption and contamination. Storage conditions should maintain a temperature below 25°C and humidity levels below 60% to ensure stability and prolong shelf life.