Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate | CAS No. 321596-55-8
Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate
Basic Information
CAS Number
321596-55-8
Molecular Formula
C7H5Br2NO3
Molecular Weight
310.93 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- Methyl 4,6-dibromo-3-hydroxypicolinate
- 2-PYRIDINECARBOXYLIC ACID, 4,6-DIBROMO-3-HYDROXY-, METHYL ESTER
- methyl 4,6-dibromo-3-hydroxypyridine-2-carboxylate
MDL Number
MFCD19440848
FAQ
What are the physical and chemical properties of Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate (CAS: 321596-55-8)?
Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate is a crystalline compound with a molecular weight of approximately 366.04 g/mol. It has limited water solubility and moderate solubility in organic solvents. This compound is highly reactive, particularly with nucleophiles and reducing agents. It exhibits strong acidity due to the hydroxy group, and the bromine substituents make it a good leaving group in nucleophilic substitution reactions.
How is Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate (CAS: 321596-55-8) typically synthesized?
Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate can be synthesized through the bromination of 3-hydroxy-2-pyridinecarboxylic acid methyl ester using N-bromosuccinimide (NBS) in the presence of a radical initiator such as benzoyl peroxide. This method provides good yields and high selectivity for the bromination at the 4,6 positions.
What industries use Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate (CAS: 321596-55-8)?
Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate is primarily used in the pharmaceutical and fine chemical industries. It serves as a precursor for the synthesis of various compounds used in drug development, particularly those requiring halogenated pyridine derivatives. Its use in the semiconductor and sensor industries is less common but may be applied in specialized applications requiring specific chemical functionalities.
What precautions should be taken when handling Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate (CAS: 321596-55-8)?
When handling Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or with the use of a fume hood due to its potential to release toxic fumes. In case of a spill, it is important to clean up the area using appropriate absorbents and clean up procedures, following the Safety Data Sheet (SDS) guidelines for proper disposal.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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