Compound Q&A
How is Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate (CAS: 321596-55-8) typically synthesized?
Answer
Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate can be synthesized through the bromination of 3-hydroxy-2-pyridinecarboxylic acid methyl ester using N-bromosuccinimide (NBS) in the presence of a radical initiator such as benzoyl peroxide. This method provides good yields and high selectivity for the bromination at the 4,6 positions.
About
CAS No
321596-55-8
English Name
Methyl 4,6-dibromo-3-hydroxy-2-pyridinecarboxylate
Molecular Formula
C7H5Br2NO3
Molecular Weight
310.93 g/mol
SMILES
COC(=O)c1nc(Br)cc(c1O)Br
InChIKey
WNFLHCVLPYFOGW-UHFFFAOYSA-N
Last Updated: 2026-01-01 01:49
