2,4-Difluorophenylalanine

Basic Information

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CAS Number

32133-35-0

Molecular Formula

C9H9F2NO2

Molecular Weight

201.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

224 °C

Boiling Point

306.1℃ at 760 mmHg

SMILES

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C1=CC(=C(C=C1F)F)CC(C(=O)O)N

InChI

InChI=1S/C9H9F2NO2/c10-6-2-1-5(7(11)4-6)3-8(12)9(13)14/h1-2,4,8H,3,12H2,(H,13,14)

InChIKey

UEFLPVKMPDEMFW-UHFFFAOYSA-N

LogP

0.9191999999999998

Topological Polar Surface Area

63.31999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

213

Safety Information

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Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

MFCD00061302
AB16790
HY-W006430
AKOS032963162
2-amino-3-(2,4-difluorophenyl)propanoic Acid
L-Phenylalanine,2,4-difluoro-
A818534
EN300-1827097
D-2,4-DIFLUOROPHE
L-2,4-DIFLUOROPHE
A821163
DTXSID70371794
2-azanyl-3-[2,4-bis(fluoranyl)phenyl]propanoic acid
2,4-Difluoro-DL-phenylalanine
BCP10482
AKOS000195276
PS-6485
FT-0656290
32133-35-0
CS-W006430
SCHEMBL44972
FT-0610100
2-amino-3-(2,4-difluorophenyl)propanoicAcid
AB02418
dl-2,4-Difluorophenylalanine
FT-0654380
AB33470
AC-14972
SY044824
2-Amino-3-(2,4-difluorophenyl)propanoic acid
2,4-DIFLUORO-DL-PHENYLALANINE

MDL Number

MFCD00061302

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 2,4-Difluorophenylalanine (CAS: 32133-35-0)?

2,4-Difluorophenylalanine is a white crystalline solid with a molecular weight of 213.04 g/mol. It is sparingly soluble in water and ethanol. The compound reacts with bases to form a salt, and can undergo substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from moisture and heat.

How is 2,4-Difluorophenylalanine (CAS: 32133-35-0) typically synthesized?

2,4-Difluorophenylalanine can be synthesized via the coupling of 2,4-difluorophenyl isocyanate with alanine. The reaction is catalyzed by a Lewis acid such as aluminum chloride, and proceeds with moderate to high selectivity and yield. It can also be prepared by the reaction of 2,4-difluorophenyl isothiocyanate with sodium enolates.

What industries use 2,4-Difluorophenylalanine (CAS: 32133-35-0)?

2,4-Difluorophenylalanine is used in pharmaceuticals for the synthesis of drugs, and in polymers for the development of novel materials. It is also utilized in the production of sensors for detecting specific compounds, and can be used in semiconductor manufacturing as a precursor.

What precautions should be taken when handling 2,4-Difluorophenylalanine (CAS: 32133-35-0)?

When handling 2,4-difluorophenylalanine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The material should be handled in a well-ventilated area or a fume hood to minimize inhalation. Spills should be cleaned up immediately using appropriate absorbents and waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.