2,4-Difluorophenylalanine(CAS: 32133-35-0)

2,4-Difluorophenylalanine is a white crystalline solid with a molecular weight of 213.04 g/mol. It is sparingly soluble in water and ethanol. The compound reacts with bases to form a salt, and can undergo substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from moisture and heat.

2,4-Difluorophenylalanine can be synthesized via the coupling of 2,4-difluorophenyl isocyanate with alanine. The reaction is catalyzed by a Lewis acid such as aluminum chloride, and proceeds with moderate to high selectivity and yield. It can also be prepared by the reaction of 2,4-difluorophenyl isothiocyanate with sodium enolates.

2,4-Difluorophenylalanine is used in pharmaceuticals for the synthesis of drugs, and in polymers for the development of novel materials. It is also utilized in the production of sensors for detecting specific compounds, and can be used in semiconductor manufacturing as a precursor.

When handling 2,4-difluorophenylalanine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The material should be handled in a well-ventilated area or a fume hood to minimize inhalation. Spills should be cleaned up immediately using appropriate absorbents and waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.