Gatifloxacin mesylate

Basic Information

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CAS Number

316819-28-0

Molecular Formula

C20H26FN3O7S

Molecular Weight

471.51 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

SMILES

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CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F.CS(=O)(=O)O

InChI

InChI=1S/C19H22FN3O4.CH4O3S/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26;1-5(2,3)4/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26);1H3,(H,2,3,4)

InChIKey

PMMNVFFMFJMFDB-UHFFFAOYSA-N

LogP

1.4844000000000004

Topological Polar Surface Area

138.17000000000002 Å²

Hydrogen Bond Donor/Acceptor

3 / 10

Complexity

745

Synonyms & References

English

Gatifloxacin mesylate
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid,methanesulfonic acid
AM 1155 mesylate
BMS 206584-01 mesylate
PD 135432 mesylate
316819-28-0
1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound with methanesulfonic acid (1:1)
DTXSID60581345
AKOS016013334
UNII-NZE1V6L7F9
HY-10581B
Gatifloxacin (mesylate)
Gatifloxacin mesylate [WHO-DD]
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;methanesulfonic acid
NZE1V6L7F9
AM-1155 (mesylate);BMS-206584 (mesylate);PD135432 (mesylate)
Gatifloxacin mesilate
1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid--methanesulfonic acid (1/1)
BCP28521
SCHEMBL18279977
Q27285122
CS-1843
C15564
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate

MDL Number

MFCD09954660

FAQ

What are the physical and chemical properties of Gatifloxacin mesylate (CAS: 316819-28-0)?

Gatifloxacin mesylate (CAS: 316819-28-0) is a crystalline compound with a molecular weight of approximately 550.74 g/mol. It is slightly soluble in water and has a higher solubility in organic solvents. The compound is chemically stable, with limited reactivity under normal storage conditions. It decomposes above 250°C.

How is Gatifloxacin mesylate (CAS: 316819-28-0) typically synthesized?

Gatifloxacin mesylate (CAS: 316819-28-0) is synthesized by reacting gatifloxacin with methanesulfonyl chloride in the presence of a base like triethylamine. The reaction is typically carried out in a solvent such as dichloromethane. The yield is generally high, and the product undergoes purification by recrystallization.

What industries use Gatifloxacin mesylate (CAS: 316819-28-0)?

Gatifloxacin mesylate (CAS: 316819-28-0) is primarily used in the pharmaceutical industry. It is an important ingredient in ophthalmic medications for the treatment of bacterial keratitis and other eye infections. It is not commonly used in other industries such as polymers, sensors, or semiconductors.

What precautions should be taken when handling Gatifloxacin mesylate (CAS: 316819-28-0)?

When handling Gatifloxacin mesylate (CAS: 316819-28-0), it is essential to use proper personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight and heat. In case of a spill, immediately contain and clean up the area using appropriate absorbent materials. Refer to the safety data sheet (SDS) for detailed information and emergency procedures.