2-Amino-5-pyrimidinecarboxylic acid

Basic Information

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CAS Number

3167-50-8

Molecular Formula

C5H5N3O2

Molecular Weight

139.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Boiling Point

474.6°C at 760 mmHg

Density

1.534

Flash Point

240.82℃

Refractive Index

1.663

SMILES

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C1=C(C=NC(=N1)N)C(=O)O

InChI

InChI=1S/C5H5N3O2/c6-5-7-1-3(2-8-5)4(9)10/h1-2H,(H,9,10)(H2,6,7,8)

InChIKey

CBRLWSXYXSFYSP-UHFFFAOYSA-N

LogP

-0.24299999999999994

Topological Polar Surface Area

89.10000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

131

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

CBRLWSXYXSFYSP-UHFFFAOYSA-N
3167-50-8
CHEMBL3322885
PS-5722
2-Amino-pyrimidine-5-carboxylic acid
2-aminopyrimidine-5-carboxylic acid, AldrichCPR
FT-0600124
2-AMINO-5-PYRIMIDINECARBOXYLIC ACID
SY013230
AB22915
AC-23145
2-aminopyrimidine-5-carboxylic Acid
2-Aminopyrimidine-5-carboxylicacid
CS-W003257
EN300-98981
AMY1915
Z274575484
MFCD05864791
J-508077
AKOS000283943
DTXSID70427245
BCP27193
5-PYRIMIDINECARBOXYLIC ACID, 2-AMINO-
SCHEMBL186175
2-Aminopyrimidine-5-carboxylic acid
2-Amino-5-carboxypyrimidine
2-aminopyrimidine-5-carboxylic acid

MDL Number

MFCD05864791

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 2-Amino-5-pyrimidinecarboxylic acid (CAS: 3167-50-8)?

2-Amino-5-pyrimidinecarboxylic acid is a white crystalline solid with a molecular weight of approximately 145.14 g/mol. It is slightly soluble in water and has a pKa of 4.7. The compound is known for its reactivity, particularly in nucleophilic substitution reactions and condensation reactions.

How is 2-Amino-5-pyrimidinecarboxylic acid (CAS: 3167-50-8) typically synthesized?

2-Amino-5-pyrimidinecarboxylic acid is typically synthesized via the condensation of 5-Amino-2-carboxypyrimidine with amines. Commonly used catalysts include strong acids such as trifluoroacetic acid. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity.

What industries use 2-Amino-5-pyrimidinecarboxylic acid (CAS: 3167-50-8)?

2-Amino-5-pyrimidinecarboxylic acid is primarily used in the pharmaceutical industry as an intermediate for the synthesis of drugs. It also finds applications in the polymer industry for the development of functional materials, and in the electronics sector for the fabrication of semiconductor materials and sensors.

What precautions should be taken when handling 2-Amino-5-pyrimidinecarboxylic acid (CAS: 3167-50-8)?

When handling 2-Amino-5-pyrimidinecarboxylic acid, it is important to use personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. The compound should be stored in a dry, cool place, away from incompatible materials. In case of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.