2,4-Dihydroxybenzamide

Basic Information

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CAS Number

3147-45-3

Molecular Formula

C7H7NO3

Molecular Weight

153.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

228°C

Boiling Point

455.8°Cat760mmHg

Density

1.458

Flash Point

229.4°C

Refractive Index

1.664

SMILES

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C1=CC(=C(C=C1O)O)C(=O)N

InChI

InChI=1S/C7H7NO3/c8-7(11)5-2-1-4(9)3-6(5)10/h1-3,9-10H,(H2,8,11)

InChIKey

IIUJCQYKTGNRHH-UHFFFAOYSA-N

LogP

0.1967000000000001

Topological Polar Surface Area

83.55 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

160

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

4-Hydroxysalicylamide
AS-15438
InChI=1/C7H7NO3/c8-7(11)5-2-1-4(9)3-6(5)10/h1-3,9-10H,(H2,8,11)
3147-45-3
NSC 60728
DTXSID8062868
MFCD00064913
CS-0197141
2,4-bis(oxidanyl)benzamide
SCHEMBL1329143
NLZ
AC-8708
NSC-60728
V2QA7KU4DZ
IIUJCQYKTGNRHH-UHFFFAOYSA-
1,3,4-Resorcylic acid amide
SB75822
FT-0634697
2,4-Dihydroxybenzamide
IIUJCQYKTGNRHH-UHFFFAOYSA-N
.beta.-Resorcylamide
1,4-Resorcylic acid amide
NS00029106
2,4-dihydroxybenzoic acid amide
Benzamide, 2,4-dihydroxy-
D3460
W-106898
A820869
SY053297
AKOS006345205
EINECS 221-567-2

MDL Number

MFCD00064913

Customs Code

29182990

FAQ

What are the physical and chemical properties of 2,4-Dihydroxybenzamide (CAS: 3147-45-3)?

2,4-Dihydroxybenzamide is a white crystalline solid with a molecular weight of approximately 172.15 g/mol. It has a melting point of 198-200°C and is soluble in water and organic solvents. The compound is moderately reactive, particularly towards acid and base catalysis, and can undergo amide hydrolysis under basic conditions.

How is 2,4-Dihydroxybenzamide (CAS: 3147-45-3) typically synthesized?

2,4-Dihydroxybenzamide is typically synthesized by the reaction of 2,4-dihydroxybenzoic acid with ammonia or an amine. This process involves condensation under basic conditions. Commonly, the synthesis involves using potassium hydroxide as a catalyst and requires controlled temperature and pH conditions to achieve high yield and selectivity.

What industries use 2,4-Dihydroxybenzamide (CAS: 3147-45-3)?

2,4-Dihydroxybenzamide finds applications in various industries. It is used in the pharmaceutical sector for its potential as a precursor in the synthesis of other compounds. In the polymer industry, it can act as a stabilizer or additive. Additionally, it is used in sensor technology for its reactivity and in semiconductor applications for its electronic properties.

What precautions should be taken when handling 2,4-Dihydroxybenzamide (CAS: 3147-45-3)?

When handling 2,4-Dihydroxybenzamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or within a fume hood to avoid inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.