2,4-Dihydroxybenzamide(CAS: 3147-45-3)

2,4-Dihydroxybenzamide is a white crystalline solid with a molecular weight of approximately 172.15 g/mol. It has a melting point of 198-200°C and is soluble in water and organic solvents. The compound is moderately reactive, particularly towards acid and base catalysis, and can undergo amide hydrolysis under basic conditions.

2,4-Dihydroxybenzamide is typically synthesized by the reaction of 2,4-dihydroxybenzoic acid with ammonia or an amine. This process involves condensation under basic conditions. Commonly, the synthesis involves using potassium hydroxide as a catalyst and requires controlled temperature and pH conditions to achieve high yield and selectivity.

2,4-Dihydroxybenzamide finds applications in various industries. It is used in the pharmaceutical sector for its potential as a precursor in the synthesis of other compounds. In the polymer industry, it can act as a stabilizer or additive. Additionally, it is used in sensor technology for its reactivity and in semiconductor applications for its electronic properties.

When handling 2,4-Dihydroxybenzamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or within a fume hood to avoid inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.