(3-Fluoro-2-pyridinyl)methanol

Basic Information

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CAS Number

31181-79-0

Molecular Formula

C6H6FNO

Molecular Weight

127.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

194.3±25.0 ºC (760 Torr),

Flash Point

71.3±23.2 ºC,

SMILES

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C1=CC(=C(N=C1)CO)F

InChI

InChI=1S/C6H6FNO/c7-5-2-1-3-8-6(5)4-9/h1-3,9H,4H2

InChIKey

FKTCIWBKNWUDAX-UHFFFAOYSA-N

LogP

0.7130000000000001

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

89.1

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

PB22208
AC-27969
31181-79-0
CHEBI:194804
AKOS006282332
3-Fluoro-2-(hydroxymethyl)pyridine
2-Hydroxymethyl-3-fluoropyridine
(3-fluoro-pyridin-2-yl)-methanol
(3-luoropyridin-2-yl)methanol
MFCD09025826
SY037894
(3-fluoropyrid-2-yl)methanol
CS-0031358
GF-0219
J-501213
BCP15521
SCHEMBL1758547
(3-Fluoropyrid-2-yl)methanol;3-Fluoro-2-(hydroxymethyl)pyridine
2-PYRIDINEMETHANOL, 3-FLUORO-
FT-0648534
A820746
FKTCIWBKNWUDAX-UHFFFAOYSA-N
(3-fluoropyridin-2-yl)methanol
3-FLUORO-2-PYRIDINEMETHANOL
AM20051058
DTXSID40599342
EN300-1654866
(3-FLUOROPYRID-2-YL)METHANOL
(3-Fluoropyridin-2-yl)methanol
2-Pyridinemethanol,3-fluoro-
3-Fluoropyrid-2-yl-methanol

MDL Number

MFCD09025826

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0)?

(3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0) is a colorless liquid with a molecular weight of approximately 151.11 g/mol. It has a low solubility in water but is more soluble in organic solvents. Chemically, it is relatively stable but can undergo nucleophilic substitution reactions. It crystallizes in the monoclinic system and has a melting point of about 10°C and a boiling point of around 180°C.

How is (3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0) typically synthesized?

(3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0) is often synthesized via the reaction of 2-fluoropyridine with methanol. Commonly, this reaction is conducted under mild conditions using a phase-transfer catalyst. The yield is generally high, with good selectivity towards the desired product.

What industries use (3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0)?

(3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It also finds applications in the polymer industry, where it can be used to modify the properties of polymers. Additionally, it has potential uses in the development of sensors and semiconductors.

What precautions should be taken when handling (3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0)?

When handling (3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0), it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly decontaminated. Always refer to the Material Safety Data Sheet (MSDS/SDS) for specific safety guidelines.