(3-Fluoro-2-pyridinyl)methanol(CAS: 31181-79-0)

(3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0) is a colorless liquid with a molecular weight of approximately 151.11 g/mol. It has a low solubility in water but is more soluble in organic solvents. Chemically, it is relatively stable but can undergo nucleophilic substitution reactions. It crystallizes in the monoclinic system and has a melting point of about 10°C and a boiling point of around 180°C.

(3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0) is often synthesized via the reaction of 2-fluoropyridine with methanol. Commonly, this reaction is conducted under mild conditions using a phase-transfer catalyst. The yield is generally high, with good selectivity towards the desired product.

(3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It also finds applications in the polymer industry, where it can be used to modify the properties of polymers. Additionally, it has potential uses in the development of sensors and semiconductors.

When handling (3-Fluoro-2-pyridinyl)methanol (CAS: 31181-79-0), it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly decontaminated. Always refer to the Material Safety Data Sheet (MSDS/SDS) for specific safety guidelines.