5-Hydroxy-3,4-dihydro-2(1H)-quinolinone

Basic Information

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CAS Number

30389-33-4

Molecular Formula

C9H9NO2

Molecular Weight

163.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

239.0 to 243.0 deg-C

Boiling Point

381.2°C at 760 mmHg

SMILES

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C1CC(=O)NC2=C1C(=CC=C2)O

InChI

InChI=1S/C9H9NO2/c11-8-3-1-2-7-6(8)4-5-9(12)10-7/h1-3,11H,4-5H2,(H,10,12)

InChIKey

UTTJAIFHRUAFED-UHFFFAOYSA-N

LogP

1.2768999999999997

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

193

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MFCD01862194
5-hydroxy-3,4-dihydro-1h-quinolin-2-one
5-hydroxy-1,2,3,4-tetrahydroquinolin-2-one
A22238
J-517603
3,4-dihydro-5-hydroxycarbostyril
AC-947
3,4-dihydro-5-hydroxy-1h-quinolin-2-one
FT-0657926
3,4-dihydro-5-hydroxyquinolin-2(1H)-one
5-Hydroxy-3,4-dihydro-2-quinoline
5-hydroxydihydro-carbostyril
DS-15129
5-hydroxy-3,4-dihydrocarbostyril
5-hydroxy-3,4-dihydroquinolin-2(1H)-one
D5669
30389-33-4
AMY40276
5-Hydroxy-3 pound not4-dihydroquinolin-2(1H)-one
5-Hydroxy-3,4-dihydro-2(1H)-quinolinone
CHEBI:183892
CARTEOLOL HYDROCHLORIDE IMPURITY B [EP IMPURITY]
SCHEMBL98299
2(1H)-Quinolinone, 3,4-dihydro-5-hydroxy-
DTXSID20184472
BCP13339
5-hydroxy-1,2,3,4-tetrahydro-2-quinolinone
hydroxy-3,4-dihydro-2-quinoline
EN300-6746809
5-hydroxy-3,4-dihydro-carbostyril
NS00028918

MDL Number

MFCD01862194

Customs Code

2933790090

FAQ

What are the physical and chemical properties of 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone (CAS: 30389-33-4)?

5-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a white solid with a molecular weight of approximately 180.23 g/mol. It has poor water solubility but is soluble in organic solvents like ethanol and acetonitrile. The compound is moderately reactive towards bases and oxidizing agents. It is stable under normal conditions but should be stored in a dry, cool place to avoid degradation.

How is 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone (CAS: 30389-33-4) typically synthesized?

5-Hydroxy-3,4-dihydro-2(1H)-quinolinone is commonly synthesized via a condensation reaction between 2-chloro-3,4-dihydro-2H-quinolinone and sodium hydroxide. The reaction typically yields a high purity product with good selectivity. The process requires mild conditions and is carried out under air-free conditions to avoid side reactions.

What industries use 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone (CAS: 30389-33-4)?

5-Hydroxy-3,4-dihydro-2(1H)-quinolinone is used in the pharmaceutical industry for the synthesis of bioactive compounds, particularly in the development of antifungal and antimicrobial agents. It also finds applications in the polymer industry as a precursor for functional polymers and in the semiconductor industry as a dopant material for electronic devices.

What precautions should be taken when handling 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone (CAS: 30389-33-4)?

When handling 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The material should be handled in a well-ventilated area or under a fume hood to avoid inhalation of dust. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.