5-Hydroxy-3,4-dihydro-2(1H)-quinolinone(CAS: 30389-33-4)

5-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a white solid with a molecular weight of approximately 180.23 g/mol. It has poor water solubility but is soluble in organic solvents like ethanol and acetonitrile. The compound is moderately reactive towards bases and oxidizing agents. It is stable under normal conditions but should be stored in a dry, cool place to avoid degradation.

5-Hydroxy-3,4-dihydro-2(1H)-quinolinone is commonly synthesized via a condensation reaction between 2-chloro-3,4-dihydro-2H-quinolinone and sodium hydroxide. The reaction typically yields a high purity product with good selectivity. The process requires mild conditions and is carried out under air-free conditions to avoid side reactions.

5-Hydroxy-3,4-dihydro-2(1H)-quinolinone is used in the pharmaceutical industry for the synthesis of bioactive compounds, particularly in the development of antifungal and antimicrobial agents. It also finds applications in the polymer industry as a precursor for functional polymers and in the semiconductor industry as a dopant material for electronic devices.

When handling 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The material should be handled in a well-ventilated area or under a fume hood to avoid inhalation of dust. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.