O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate

Basic Information

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CAS Number

29232-93-7

Molecular Formula

C11H20N3O3PS

Molecular Weight

305.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

15 ºC

Boiling Point

386.5 °C at 760 mmHg

Flash Point

-18 °C

Refractive Index

nD25 1.527

SMILES

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CCN(CC)C1=NC(OP(=S)(OC)OC)=CC(C)=N1

InChI

InChI=1S/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3

InChIKey

QHOQHJPRIBSPCY-UHFFFAOYSA-N

LogP

2.5273200000000005

Topological Polar Surface Area

56.71000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 6

Complexity

310

Safety Information

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GHS Hazard Pictograms

H302

H410

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Sensitiveness

对光敏感

Synonyms & References

English

Pirimiphos-methyl
O-(2-(Diethylamino)-6-methyl-4-pyrimidinyl)-O,O-dimethyl phosphorothioate
Actellic
Actellifog
Dimethyl O-(2-(diethylamino)-6-methyl-4-pyrimidinyl)phosphorothioate
Blex
Methylpyrimiphos
Pirimifosmethyl
Pirimiphos-Me
Plant Protection
PP511
Pyrimidinol, 2-(diethylamino)-6-methyl-, O-ester with O,O-dimethyl phosphorothioate
Silosan
Tomahawk
Pirimiphos-methyl solution
Pirimiphos Methyl
Pirimiphos-methyl Standard
Pirimiphos-methyl, 9
Actelic
aktelik
O,O-dimethyl-O-(2-diethyl-amino-6-methylpyrimidine-4-yl)
O-[2-(diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate
O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dime
O-2-diethylamino-6-methylpyrimidin-4-yl O,O-dimethyl phosphorothioate
O-2-diethylamino-6-methylpyrimidin-4-yl-O,O-dimethylphosphorothioate
oms1424
pirimifos-methyl
Sybol
sybol2
O-(2-Diethylamino-6-methyl-4-pyrimidinyl)-O,O-dimethyl phosphorothioate

MDL Number

MFCD00055366

Customs Code

2933599011

FAQ

What are the physical and chemical properties of O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate (CAS: 29232-93-7)?

The compound has a crystalline form with a molecular weight of approximately 428.59 g/mol. It is poorly soluble in water but soluble in common organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It has a melting point of around 165°C and is stable at room temperature but requires protection from moisture and air to prevent degradation.

How is O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate (CAS: 29232-93-7) typically synthesized?

The compound is typically synthesized via the phosphorothioylation of a dimethyl pyrimidine derivative using diethylamine. The reaction involves the use of a base like triethylamine and is carried out in an appropriate organic solvent. The selectivity and yield are high, with the product isolated by column chromatography and further purified by recrystallization.

What industries use O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate (CAS: 29232-93-7)?

This compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also found in the agricultural sector as a pesticide component. Additionally, it has applications in the polymer industry for enhancing certain properties of polymers and in sensor technology for detection purposes.

What precautions should be taken when handling O-[2-(Diethylamino)-6-methyl-4-pyrimidinyl] O,O-dimethyl phosphorothioate (CAS: 29232-93-7)?

When handling this compound, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation or skin contact. Spills should be cleaned up immediately with appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.