2,5-Dichlorobenzoyl chloride

Basic Information

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CAS Number

2905-61-5

Molecular Formula

C7H3Cl3O

Molecular Weight

209.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

30°C

Boiling Point

95°C/1mmHg

Density

1.498

Flash Point

23 °C

Refractive Index

1.576

SMILES

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C1=CC(=C(C=C1Cl)C(=O)Cl)Cl

InChI

InChI=1S/C7H3Cl3O/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H

InChIKey

RSINFFVFOTUDEC-UHFFFAOYSA-N

LogP

3.3724000000000007

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

160

Safety Information

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Hazard Statement

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

2,5-dichlorobenzoic chloride
2,5-DICHLOROBENZOYL CHLORIDE [HSDB]
NSC 41887
2,5-dichlorobenzoylchoride
2,5-dichlorobenzoic acid chloride
2,5-Dichlorobenzoyl chloride, AldrichCPR
RSINFFVFOTUDEC-UHFFFAOYSA-N
UNII-F7C0V01SK6
Benzoyl chloride, 2,5-dichloro-
Q27277761
EINECS 220-812-0
D2953
A819743
2,5-bis(chloranyl)benzoyl chloride
NS00028617
2,5-dichlorobenzoyl-chloride
D90136
F7C0V01SK6
2,5-DICHLOROBENZOYL CHLORIDE
NSC-41887
F2146-0392
HSDB 5902
Benzoyl chloride,5-dichloro-
NSC41887
Q-200194
2905-61-5
AKOS009218476
MFCD00035821
EN300-399450
DTXSID4062698
SCHEMBL699001

MDL Number

MFCD00035821

Customs Code

2916399090

FAQ

What are the physical and chemical properties of 2,5-Dichlorobenzoyl chloride (CAS: 2905-61-5)?

2,5-Dichlorobenzoyl chloride is a yellow to amber-colored liquid at room temperature. It has a molecular weight of approximately 228.04 g/mol. It is soluble in common organic solvents like ethanol and acetone but has limited water solubility. Chemically, it is highly reactive due to the presence of chlorine substituents and the electrophilic character of the benzoyl group.

How is 2,5-Dichlorobenzoyl chloride (CAS: 2905-61-5) typically synthesized?

2,5-Dichlorobenzoyl chloride is typically synthesized by the reaction of 2,5-dichlorobenzoic acid with thionyl chloride. Commonly, thionyl chloride is added to a solution of 2,5-dichlorobenzoic acid and the mixture is heated under reflux to enhance the reaction. The yield is generally high, and the process is conducted under mild conditions to avoid overoxidation of the aromatic ring.

What industries use 2,5-Dichlorobenzoyl chloride (CAS: 2905-61-5)?

2,5-Dichlorobenzoyl chloride finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also used in the polymer industry for the production of functionalized polymers. Additionally, it has applications in the semiconductor industry for specific chemical vapor deposition processes and in the manufacturing of sensors for detecting various gases.

What precautions should be taken when handling 2,5-Dichlorobenzoyl chloride (CAS: 2905-61-5)?

When handling 2,5-Dichlorobenzoyl chloride, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be neutralized with a base and then cleaned up, and all waste should be disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.