4-Benzyl-2-hydroxy-3-morpholinone

Basic Information

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CAS Number

287930-73-8

Molecular Formula

C11H13NO3

Molecular Weight

207.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

134.0 to 138.0 deg-C

Boiling Point

441.7°C at 760 mmHg

Density

1.292

Flash Point

220.943°C

Refractive Index

1.595

SMILES

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C1COC(C(=O)N1CC2=CC=CC=C2)O

InChI

InChI=1S/C11H13NO3/c13-10-11(14)15-7-6-12(10)8-9-4-2-1-3-5-9/h1-5,11,14H,6-8H2

InChIKey

CAGSEMPCDRYWFN-UHFFFAOYSA-N

LogP

0.36380000000000007

Topological Polar Surface Area

49.769999999999996 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

226

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

MFCD07776435
287930-73-8
DW732HYZ43
A847849
CS-0156281
J-514479
B4918
Benzyl-2-hydroxymorpholin-3-one
SCHEMBL12208454
BCP08642
Y10237
AKOS015918357
FT-0647045
4-benzyl-2-hydroxy-morpholin-3-one
3-Morpholinone, 2-hydroxy-4-(phenylmethyl)-
AB42365
AC-8191
4-Benzyl-2-hydroxymorpholin-3-one
2-HYDROXY-4-(PHENYLMETHYL)-3-MORPHOLINONE
DTXSID60433133
DS-12564
3-Morpholinone,2-hydroxy-4-(phenylMethyl)-
2-Hydroxy-4-(phenylMethyl)-3-Morpholinone
4-Benzyl-2-hydroxy-morpholin-3-one
benzyl lactam lactol
KSC496I1B
FCH1734215
ST2405563
AX8094400
AB0023976
W5143

MDL Number

MFCD07776435

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-Benzyl-2-hydroxy-3-morpholinone (CAS: 287930-73-8)?

4-Benzyl-2-hydroxy-3-morpholinone is a crystalline compound with a molecular weight of approximately 269.34 g/mol. It has a solubility of about 0.5 g/100 mL in water and exhibits moderate reactivity with basic compounds. The compound is soluble in common organic solvents like ethanol and acetone. It is stable under normal conditions but can degrade in strongly acidic or basic environments.

How is 4-Benzyl-2-hydroxy-3-morpholinone (CAS: 287930-73-8) typically synthesized?

4-Benzyl-2-hydroxy-3-morpholinone is typically synthesized via a multi-step process starting from morpholine and benzyl alcohol. The reaction involves the formation of an ester intermediate, followed by hydrolysis and deprotection. This process requires the use of appropriate solvents and mild basic conditions to achieve high yield and selectivity.

What industries use 4-Benzyl-2-hydroxy-3-morpholinone (CAS: 287930-73-8)?

4-Benzyl-2-hydroxy-3-morpholinone is primarily used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It also finds applications in the polymer industry for the production of functionalized polymers, and in the sensor technology sector for the development of specific chemical sensors and semiconductors.

What precautions should be taken when handling 4-Benzyl-2-hydroxy-3-morpholinone (CAS: 287930-73-8)?

When handling 4-Benzyl-2-hydroxy-3-morpholinone, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to avoid inhalation of vapors. In case of spillage, immediate cleanup is required using appropriate absorbents, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed emergency procedures and storage guidelines.