1-(Trifluoromethyl)cyclopropanecarboxylic acid

Basic Information

View in Editor

CAS Number

277756-46-4

Molecular Formula

C5H5F3O2

Molecular Weight

154.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

86.0 to 90.0 deg-C

Boiling Point

184°C

Flash Point

182-184°C

SMILES

View in Editor

C1CC1(C(=O)O)C(F)(F)F

InChI

InChI=1S/C5H5F3O2/c6-5(7,8)4(1-2-4)3(9)10/h1-2H2,(H,9,10)

InChIKey

SKCBKBCACWDALV-UHFFFAOYSA-N

LogP

1.4135

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

168

Safety Information

View Safety Information

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

1-trifluoromethyl-cyclopropanecarboxylic acid
1-(trifluoromethyl)-cyclopropanecarboxylic acid
1-(trifluoromethyl)cyclopropan-1-carboxylic acid
Trifluoromethyl-cyclopropanecarboxylic acid
1-(trifluoromethyl)-1-cyclopropanecarboxylic acid
1-trifluormethyl-cyclopropanecarboxylic acid
1-(trifluoromethyl)cyclopropanecarboxylic acid
A5342
1-(trifluoromethyl)cyclopropane carboxylic acid
1-trifluoromethyl-cyclopropane carboxylic acid
Trifluoromethyl cyclopropane carboxylic acid
FT-0608323
1-(trifluoromethyl)cyclopropanecarboxylic acid;1-TRIFLUOROMETHYLCYCLOPROPANECARBOXYLIC ACID
AM803625
EN300-64916
DTXSID80380857
J-503685
C5H5F3O2
BCP05999
T3765
PS-6587
1-(Trifluoromethyl)cyclopropanecarboxylicacid
1-Trifluoromethylcyclopropane-1-carboxylic acid
AKOS005063378
CYCLOPROPANECARBOXYLIC ACID, 1-(TRIFLUOROMETHYL)-
CS-0020140
MFCD03093070
1-(Trifluoromethyl)cyclopropane-1-carboxylic acid
277756-46-4
1-(Trifluoromethyl)cyclopropane-1-carboxylicacid
1-trifluoromethylcyclopropanecarboxylic acid

MDL Number

MFCD03093070

Customs Code

2916209090

FAQ

What are the physical and chemical properties of 1-(Trifluoromethyl)cyclopropanecarboxylic acid (CAS: 277756-46-4)?

1-(Trifluoromethyl)cyclopropanecarboxylic acid has a crystalline form and a molecular weight of approximately 203.11 g/mol. It is poorly water-soluble but soluble in organic solvents like ethanol and acetone. It shows moderate reactivity, particularly in nucleophilic substitution reactions. Its chemical properties include resistance to hydrolysis and stability under normal conditions.

How is 1-(Trifluoromethyl)cyclopropanecarboxylic acid (CAS: 277756-46-4) typically synthesized?

1-(Trifluoromethyl)cyclopropanecarboxylic acid is often synthesized via the Wittig reaction, where trifluoromethyl ketone is reacted with a phosphonium ylide. The reaction typically yields a high selectivity for the desired product with good yield. Other methods include direct trifluoromethylation of cyclopropanecarboxylic acid derivatives.

What industries use 1-(Trifluoromethyl)cyclopropanecarboxylic acid (CAS: 277756-46-4)?

1-(Trifluoromethyl)cyclopropanecarboxylic acid finds applications in the pharmaceutical industry for the synthesis of drug intermediates, in polymer science for specific polymer modification, and in the electronics industry for the production of sensitive semiconductor materials. It is also used in the development of sensors and other specialized chemical products.

What precautions should be taken when handling 1-(Trifluoromethyl)cyclopropanecarboxylic acid (CAS: 277756-46-4)?

When handling 1-(Trifluoromethyl)cyclopropanecarboxylic acid, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with caution using appropriate absorbents, and the area should be thoroughly cleaned. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.