(3S)-3-Amino-3-(1-naphthyl)propanoic acid

Basic Information

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CAS Number

275826-46-5

Molecular Formula

C13H13NO2

Molecular Weight

215.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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N[C@@H](CC(=O)O)c1cccc2ccccc12

InChI

InChI=1S/C13H13NO2/c14-12(8-13(15)16)11-7-3-5-9-4-1-2-6-10(9)11/h1-7,12H,8,14H2,(H,15,16)/t12-/m0/s1

InChIKey

BIOQBKBTOAMMDG-LBPRGKRZSA-N

LogP

2.3143000000000002

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Synonyms & References

English

(S)-3-Amino-3-(naphthalen-1-yl)propanoic acid
(S)-3-Amino-3-(1-naphthyl)-propionic aci
(S)-3-AMINO-3-(1-NAPHTHYL)-PROPIONIC ACID
(S)- 3-Amino-3-(1-naphthylphenyl)-propionic acid
AC1MC5R7
CTK4F9925
MolPort-003-794-406
PubChem24013

MDL Number

MFCD04113670

FAQ

What are the physical and chemical properties of (3S)-3-Amino-3-(1-naphthyl)propanoic acid (CAS: 275826-46-5)?

(3S)-3-Amino-3-(1-naphthyl)propanoic acid (CAS: 275826-46-5) is a white crystalline solid with a molecular weight of approximately 264.26 g/mol. It is slightly soluble in water and ethanol. The compound exhibits basic reactivity due to the amino group. It is highly stable under neutral conditions but can hydrolyze under acidic or basic conditions.

How is (3S)-3-Amino-3-(1-naphthyl)propanoic acid (CAS: 275826-46-5) typically synthesized?

This compound is typically synthesized through a condensation reaction of 1-naphthylacetyl chloride and amino acids or amines. The reaction is usually carried out in the presence of a base like triethylamine and conducted under mild conditions. The yield is moderate to good, with high selectivity for the (3S) configuration.

What industries use (3S)-3-Amino-3-(1-naphthyl)propanoic acid (CAS: 275826-46-5)?

(3S)-3-Amino-3-(1-naphthyl)propanoic acid (CAS: 275826-46-5) is used in the pharmaceutical industry as a precursor to drug synthesis. It is also employed in the production of functional materials and in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (3S)-3-Amino-3-(1-naphthyl)propanoic acid (CAS: 275826-46-5)?

Proper handling of (3S)-3-Amino-3-(1-naphthyl)propanoic acid (CAS: 275826-46-5) requires use of protective equipment, such as gloves and goggles. It should be stored in a cool, dry place, away from strong acids and bases. In case of spill, use appropriate absorbents and follow local safety protocols. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.