4,4'-Dichloro-3,3'-bipyridine

Basic Information

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CAS Number

27353-36-2

Molecular Formula

C10H6Cl2N2

Molecular Weight

225.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

110 ºC (hexane )

SMILES

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C1=CN=CC(=C1Cl)C2=C(C=CN=C2)Cl

InChI

InChI=1S/C10H6Cl2N2/c11-9-1-3-13-5-7(9)8-6-14-4-2-10(8)12/h1-6H

InChIKey

ZOAQFXNDAZYAPH-UHFFFAOYSA-N

LogP

3.450400000000002

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

169

Synonyms & References

English

4,4'-dichloro-3,3'-bipyridine
4,4\'-dichloro-[3,3\']bipyridinyl
4-chloro-3-(4-chloropyridin-3-yl)pyridine
4,4'-dichloro-3,3'-dipyridine
4,4-Dichloro-3,3-bipyridine
AK175241
SCHEMBL2942923
CS-0096447
27353-36-2
SY117345
AKOS025405113
DS-8980
3,3'-Bipyridine, 4,4'-dichloro-
CBA35336
DA-39659
W16889
AMY7381
4,4 inverted exclamation mark -Dichloro-3,3 inverted exclamation mark -bipyridine
MFCD00137931

MDL Number

MFCD00137931

FAQ

What are the physical and chemical properties of 4,4'-Dichloro-3,3'-bipyridine (CAS: 27353-36-2)?

4,4'-Dichloro-3,3'-bipyridine is a crystalline solid with a molecular weight of 267.04 g/mol. It is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. The compound exhibits good stability in air and is less reactive towards common oxidants and reductants. It has a high melting point and a low vapor pressure.

How is 4,4'-Dichloro-3,3'-bipyridine (CAS: 27353-36-2) typically synthesized?

4,4'-Dichloro-3,3'-bipyridine is commonly synthesized via the chlorination of 3,3'-bipyridine using thionyl chloride as the chlorinating agent. The reaction is carried out in an inert atmosphere, and the yield is typically around 70-80%. This method provides good selectivity and high purity.

What industries use 4,4'-Dichloro-3,3'-bipyridine (CAS: 27353-36-2)?

4,4'-Dichloro-3,3'-bipyridine is used in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of certain drugs. It is also utilized in the production of sensors, electronic materials, and as a ligand in coordination chemistry for catalytic applications.

What precautions should be taken when handling 4,4'-Dichloro-3,3'-bipyridine (CAS: 27353-36-2)?

When handling 4,4'-Dichloro-3,3'-bipyridine, it is important to use appropriate personal protective equipment (PPE), such as gloves and safety goggles. Store the compound in a cool, dry place, away from direct sunlight and moisture. Fume hoods should be used during handling to minimize exposure. In case of a spill, dispose of it according to the Material Safety Data Sheet (MSDS) guidelines.