4,4'-Dichloro-3,3'-bipyridine(CAS: 27353-36-2)

4,4'-Dichloro-3,3'-bipyridine is a crystalline solid with a molecular weight of 267.04 g/mol. It is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. The compound exhibits good stability in air and is less reactive towards common oxidants and reductants. It has a high melting point and a low vapor pressure.

4,4'-Dichloro-3,3'-bipyridine is commonly synthesized via the chlorination of 3,3'-bipyridine using thionyl chloride as the chlorinating agent. The reaction is carried out in an inert atmosphere, and the yield is typically around 70-80%. This method provides good selectivity and high purity.

4,4'-Dichloro-3,3'-bipyridine is used in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of certain drugs. It is also utilized in the production of sensors, electronic materials, and as a ligand in coordination chemistry for catalytic applications.

When handling 4,4'-Dichloro-3,3'-bipyridine, it is important to use appropriate personal protective equipment (PPE), such as gloves and safety goggles. Store the compound in a cool, dry place, away from direct sunlight and moisture. Fume hoods should be used during handling to minimize exposure. In case of a spill, dispose of it according to the Material Safety Data Sheet (MSDS) guidelines.