6-Methoxy-2-pyridinecarboxylic acid

Basic Information

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CAS Number

26893-73-2

Molecular Formula

C7H7NO3

Molecular Weight

153.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

132.0 to 136.0 deg-C

Boiling Point

300.8℃ at 760 mmHg

Density

1.284

Water Solubility

Slightly soluble in water.

Flash Point

135.7℃

Refractive Index

1.504

SMILES

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COC1=CC=CC(=N1)C(=O)O

InChI

InChI=1S/C7H7NO3/c1-11-6-4-2-3-5(8-6)7(9)10/h2-4H,1H3,(H,9,10)

InChIKey

KSWBODXXZITTPO-UHFFFAOYSA-N

LogP

0.7883999999999999

Topological Polar Surface Area

59.42 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

149

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

FT-0638647
2-Methoxy-6-picolinicacid
AKOS005257711
MFCD06800962
6-Methoxy-2-pyridinecarboxylic acid
6-Methoxypicolinic acid
WAA07865
6-(methyloxy)-2-pyridinecarboxylic acid
CL0063
AB29993
DTXSID60341188
CS-D1581
AC-7514
SY007551
FT-0650038
6-Methoxypicolinicacid
2-Pyridinecarboxylic acid, 6-methoxy-
6-Methoxypyridine-2-carboxylic acid
2-methoxy-6-picolinic acid
TS-02030
26893-73-2
6-Methoxy-pyridine-2-carboxylic acid
6-Methoxypyridine-2-carboxylic acid, 97%
EN300-102850
Z969095262
M2189
SCHEMBL17338
J-513171
Picolinic acid, 6-methoxy-
AM20061706
A5273

MDL Number

MFCD06800962

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Methoxy-2-pyridinecarboxylic acid (CAS: 26893-73-2)?

6-Methoxy-2-pyridinecarboxylic acid is a crystalline solid with a molecular weight of approximately 175.17 g/mol. It has a melting point of 154-156°C and is slightly soluble in water. This compound is reactive towards basic conditions and susceptible to hydrolysis. It shows good solubility in polar solvents such as ethanol and acetonitrile.

How is 6-Methoxy-2-pyridinecarboxylic acid (CAS: 26893-73-2) typically synthesized?

6-Methoxy-2-pyridinecarboxylic acid is commonly synthesized via the methylation of 2-pyridinecarboxylic acid with methanol in the presence of a strong acid catalyst such as sulfuric acid. The reaction is typically carried out at room temperature, and the yield is generally around 70-80%. The product is then purified by recrystallization from aqueous solvent.

What industries use 6-Methoxy-2-pyridinecarboxylic acid (CAS: 26893-73-2)?

6-Methoxy-2-pyridinecarboxylic acid finds applications in the pharmaceutical industry, where it serves as a precursor for the synthesis of various bioactive compounds. It is also used in the production of certain sensors and functional materials for its unique chemical properties.

What precautions should be taken when handling 6-Methoxy-2-pyridinecarboxylic acid (CAS: 26893-73-2)?

When handling 6-Methoxy-2-pyridinecarboxylic acid, it is important to wear protective equipment such as gloves and goggles. Store it in a cool, dry place away from direct sunlight and heat sources. Dispose of any waste following local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.