6-Methoxy-2-pyridinecarboxylic acid(CAS: 26893-73-2)

6-Methoxy-2-pyridinecarboxylic acid is a crystalline solid with a molecular weight of approximately 175.17 g/mol. It has a melting point of 154-156°C and is slightly soluble in water. This compound is reactive towards basic conditions and susceptible to hydrolysis. It shows good solubility in polar solvents such as ethanol and acetonitrile.

6-Methoxy-2-pyridinecarboxylic acid is commonly synthesized via the methylation of 2-pyridinecarboxylic acid with methanol in the presence of a strong acid catalyst such as sulfuric acid. The reaction is typically carried out at room temperature, and the yield is generally around 70-80%. The product is then purified by recrystallization from aqueous solvent.

6-Methoxy-2-pyridinecarboxylic acid finds applications in the pharmaceutical industry, where it serves as a precursor for the synthesis of various bioactive compounds. It is also used in the production of certain sensors and functional materials for its unique chemical properties.

When handling 6-Methoxy-2-pyridinecarboxylic acid, it is important to wear protective equipment such as gloves and goggles. Store it in a cool, dry place away from direct sunlight and heat sources. Dispose of any waste following local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.