4-(5-Nitro-2-pyridinyl)morpholine

Basic Information

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CAS Number

26820-62-2

Molecular Formula

C9H11N3O3

Molecular Weight

209.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

140-142 ºC

SMILES

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C1COCCN1C2=NC=C(C=C2)[N+](=O)[O-]

InChI

InChI=1S/C9H11N3O3/c13-12(14)8-1-2-9(10-7-8)11-3-5-15-6-4-11/h1-2,7H,3-6H2

InChIKey

FYJXIPHXFGFEGT-UHFFFAOYSA-N

LogP

1.41460

Complexity

225

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

WLN: T6N DOTJ A- BT6NJ ENW
HMS2484J13
CHEMBL1569326
4-(5-nitro-2-pyridinyl)morpholine
SCHEMBL341002
SMR000178275
AM20051011
Z57184643
NSC 91094
AC-7708
MLS000568250
AKOS000334021
Oprea1_651990
BIM-0020952.P001
AB00086307-01
NSC91094
2-Morpholino-5-nitropyridine
CS-W015164
4-(5-Nitro-pyridin-2-yl)-morpholine
Morpholine, 4-(5-nitro-2-pyridyl)-
NCGC00245529-01
4-(5-nitropyridin-2-yl)morpholine
4-(5-Nitro-2-pyridyl)-morpholine
26820-62-2
Morpholine, 4-(5-nitro-2-pyridinyl)-
CBMicro_021094
NSC-91094
NCIOpen2_005510
EN300-25782
CCG-8810
MFCD00023308

MDL Number

MFCD00023308

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-(5-Nitro-2-pyridinyl)morpholine (CAS: 26820-62-2)?

4-(5-Nitro-2-pyridinyl)morpholine is a crystalline solid with a molecular weight of approximately 215.13 g/mol. It has a high solubility in organic solvents such as acetone and methanol. This compound is moderately reactive, particularly towards nucleophilic substitution reactions. It is often used in synthetic chemistry due to its structural complexity and functional groups.

How is 4-(5-Nitro-2-pyridinyl)morpholine (CAS: 26820-62-2) typically synthesized?

4-(5-Nitro-2-pyridinyl)morpholine can be synthesized by reacting morpholine with 5-nitropyridine in the presence of an appropriate base, such as sodium hydride, followed by work-up and purification. This method ensures high selectivity and yield, making it a common approach in the synthesis of this compound.

What industries use 4-(5-Nitro-2-pyridinyl)morpholine (CAS: 26820-62-2)?

4-(5-Nitro-2-pyridinyl)morpholine is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients. It also finds applications in the polymer industry for the development of advanced materials. Additionally, this compound is used in the production of sensors and as a precursor in semiconductor manufacturing processes.

What precautions should be taken when handling 4-(5-Nitro-2-pyridinyl)morpholine (CAS: 26820-62-2)?

When handling 4-(5-Nitro-2-pyridinyl)morpholine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.