4-(5-Nitro-2-pyridinyl)morpholine(CAS: 26820-62-2)

4-(5-Nitro-2-pyridinyl)morpholine is a crystalline solid with a molecular weight of approximately 215.13 g/mol. It has a high solubility in organic solvents such as acetone and methanol. This compound is moderately reactive, particularly towards nucleophilic substitution reactions. It is often used in synthetic chemistry due to its structural complexity and functional groups.

4-(5-Nitro-2-pyridinyl)morpholine can be synthesized by reacting morpholine with 5-nitropyridine in the presence of an appropriate base, such as sodium hydride, followed by work-up and purification. This method ensures high selectivity and yield, making it a common approach in the synthesis of this compound.

4-(5-Nitro-2-pyridinyl)morpholine is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients. It also finds applications in the polymer industry for the development of advanced materials. Additionally, this compound is used in the production of sensors and as a precursor in semiconductor manufacturing processes.

When handling 4-(5-Nitro-2-pyridinyl)morpholine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.