Methyl (1R,2R)-2-aminocyclohexanecarboxylate | CAS No. 267230-45-5

Methyl (1R,2R)-2-aminocyclohexanecarboxylate

Basic Information

CAS Number

267230-45-5

Molecular Formula

C8H15NO2

Molecular Weight

157.21 g/mol

AD

Basic Physical Properties

COC(=O)C1CCCCC1N

InChI

InChI=1S/C8H15NO2/c1-11-8(10)6-4-2-3-5-7(6)9/h6-7H,2-5,9H2,1H3/t6-,7-/m1/s1

InChIKey

SUYHWZRODJBJER-RNFRBKRXSA-N

LogP

0.6769

Topological Polar Surface Area

52.32 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

147

Synonyms & References

English

  • Cyclohexanecarboxylic acid, 2-amino-, methyl ester, (1R,2R)- (9CI)
  • methyl (1R, 2R)-2-aminocyclohexane-1-carboxylate
  • DTXSID20472063
  • methyl trans-2-aminocyclohexanecarboxylate
  • SCHEMBL4734308
  • 267230-45-5
  • SUYHWZRODJBJER-RNFRBKRXSA-N
  • CS-0183720
  • (1R,2R)-Methyl 2-aminocyclohexanecarboxylate
  • trans-Methyl 2-aminocyclohexanecarboxylate
  • Methyl (1R,2R)-2-aminocyclohexane-1-carboxylate
  • 161618-50-4
  • EN300-127605
  • Cyclohexanecarboxylicacid, 2-amino-, methyl ester, (1R,2R)-
  • METHYL (1R,2R)-2-AMINOCYCLOHEXANE-1-CARBOXYLATE

MDL Number

MFCD18632979

FAQ

What are the physical and chemical properties of Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5)?

Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5) is a crystalline compound with a molecular weight of approximately 174.29 g/mol. It has a pKa of about 4.73 and is slightly soluble in water. It reacts readily with bases and is known for its reactivity in amide formation. The compound is stable under normal conditions but should be stored in a dry, cool place to prevent degradation.

How is Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5) typically synthesized?

Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5) is synthesized through a multi-step process involving the reaction of cyclohexanone with ammonia, followed by methylation. Commonly, this process uses a Lewis acid catalyst such as aluminum chloride to promote the methylation step. The overall yield and selectivity can be optimized by controlling the reaction conditions and catalyst choice.

What industries use Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5)?

Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds and in polymer production for the development of novel materials. Additionally, it finds applications in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5)?

When handling Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or under a fume hood to avoid inhalation of fumes. In case of spill, neutralize with an appropriate base and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...