Compound Q&A

How is Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5) typically synthesized?

Answer

Methyl (1R,2R)-2-aminocyclohexanecarboxylate
Methyl (1R,2R)-2-aminocyclohexanecarboxylate (CAS: 267230-45-5) is synthesized through a multi-step process involving the reaction of cyclohexanone with ammonia, followed by methylation. Commonly, this process uses a Lewis acid catalyst such as aluminum chloride to promote the methylation step. The overall yield and selectivity can be optimized by controlling the reaction conditions and catalyst choice.

About

English Name Methyl (1R,2R)-2-aminocyclohexanecarboxylate
Molecular Formula C8H15NO2
Molecular Weight 157.21 g/mol
SMILES COC(=O)C1CCCCC1N
InChIKey SUYHWZRODJBJER-RNFRBKRXSA-N
Last Updated: 2026-03-04 16:30

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