2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one | CAS No. 26578-09-6
2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one
Basic Information
CAS Number
26578-09-6
Molecular Formula
C10H13N5O5
Molecular Weight
283.24 g/mol
AD
Chemical Classification
Basic Physical Properties
Density
2.258 g/cm3
Synonyms & References
English
- E78056
- AKOS037649163
- 2-AMINO-9-[(2S,3S,4R,5S)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-1H-PURIN-6-ONE
- NYHBQMYGNKIUIF-GIMIYPNGSA-N
- L-GUANOSINE
- MFCD00064103
- J-700329
- 26578-09-6
- 9-beta-L-Ribofuranosylguanine
- SCHEMBL329614
- NSC-816047
- SCHEMBL17993312
- BS-16795
- 2-Amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one
- AC-32190
- 2-amino-9-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
- NSC816047
- 2-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
- L-Guanosine
- 2-amino-9-pentofuranosyl-1,9-dihydro-purin-6-one
- β-L-GUANOSINE
- Guanine,9-b-L-ribofuranosyl- (8CI)
- guanosine
- guanine riboside
- vernine
- Guanozin
- Guanosin
- Inosine, 2-amino-
- Vernine (VAN)
- 9-beta-D-Ribofuranosylguanine
- Guanine-9-beta-D-ribofuranoside
MDL Number
MFCD00064103
FAQ
What are the physical and chemical properties of 2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one (CAS: 26578-09-6)?
2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one is a crystalline solid with a molecular weight of approximately 324.32 g/mol. It has a high solubility in water and is slightly soluble in ethanol. The compound is known for its reactivity with nucleophiles and its stability under basic conditions. It is typically used as a building block in synthetic organic chemistry.
How is 2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one (CAS: 26578-09-6) typically synthesized?
2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one is typically synthesized through a multistep process involving the ribosylation of 6-aminopurine using a beta-L-ribonucleoside. Common catalysts include organometallic reagents, and the reaction is often carried out under acidic conditions. The yield can be improved by optimizing the reaction conditions and using high-purity starting materials.
What industries use 2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one (CAS: 26578-09-6)?
2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one is used in the pharmaceutical industry as a precursor for the synthesis of nucleoside analogs, which are important for antiviral and anticancer treatments. It is also employed in the development of biosensors and in the production of nucleoside-based polymers for various applications.
What precautions should be taken when handling 2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one (CAS: 26578-09-6)?
When handling 2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area, preferably in a fume hood, and away from oxidizing agents. In case of a spill, the area should be flushed with water, and the material should be carefully cleaned up according to the safety data sheet (SDS).
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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