2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one(CAS: 26578-09-6)

2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one is a crystalline solid with a molecular weight of approximately 324.32 g/mol. It has a high solubility in water and is slightly soluble in ethanol. The compound is known for its reactivity with nucleophiles and its stability under basic conditions. It is typically used as a building block in synthetic organic chemistry.

2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one is typically synthesized through a multistep process involving the ribosylation of 6-aminopurine using a beta-L-ribonucleoside. Common catalysts include organometallic reagents, and the reaction is often carried out under acidic conditions. The yield can be improved by optimizing the reaction conditions and using high-purity starting materials.

2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one is used in the pharmaceutical industry as a precursor for the synthesis of nucleoside analogs, which are important for antiviral and anticancer treatments. It is also employed in the development of biosensors and in the production of nucleoside-based polymers for various applications.

When handling 2-Amino-9-(beta-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area, preferably in a fume hood, and away from oxidizing agents. In case of a spill, the area should be flushed with water, and the material should be carefully cleaned up according to the safety data sheet (SDS).