4-Amino-2-Methylphenol

Basic Information

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CAS Number

2635-95-2

Molecular Formula

C7H9NO

Molecular Weight

123.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

174-176 °C

SMILES

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CC1=C(C=CC(=C1)N)O

InChI

InChI=1S/C7H9NO/c1-5-4-6(8)2-3-7(5)9/h2-4,9H,8H2,1H3

InChIKey

HDGMAACKJSBLMW-UHFFFAOYSA-N

LogP

1.86400

Complexity

94.9

Synonyms & References

English

W-107050
Q27275742
2-Methyl-4-aminophenol
Phenol, 4-amino-2-methyl-
AM84881
NS00028474
2835-96-3
4-Amino-o-cresol
FT-0634418
FT-0659627
4llp
CS8D10SY5L
2635-95-2
3-Methyl-4-hydroxyaniline
o-Cresol, 4-amino-
2-methyl-p-aminophenol
5-amino-o-kresol
DTXSID2062662
4-Amino-2 methylphenol
SY021230
EINECS 220-619-1
4-azanyl-2-methyl-phenol
A818404
4ZE
4A2MP
4-Amino-2-methylphenol
3-Amino-6-hydroxytoluene
EN300-112638
AC-7841
SCHEMBL33808
4-amino-ortho-cresol

MDL Number

MFCD00007878

FAQ

What are the physical and chemical properties of 4-Amino-2-Methylphenol (CAS: 2635-95-2)?

4-Amino-2-Methylphenol is a white crystalline solid with a molecular weight of approximately 149.17 g/mol. It is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. Chemically, it is reactive and can participate in various organic reactions such as nucleophilic substitution and electrophilic aromatic substitution.

How is 4-Amino-2-Methylphenol (CAS: 2635-95-2) typically synthesized?

4-Amino-2-Methylphenol is typically synthesized through the reduction of 2-methylphenylisocyanate with sodium borohydride. The reaction is carried out under mild conditions with good yield and selectivity. Other methods may involve the direct amination of 2-methylbenzaldehyde using ammonia or an amine derivative.

What industries use 4-Amino-2-Methylphenol (CAS: 2635-95-2)?

4-Amino-2-Methylphenol is used in various industries, particularly in pharmaceuticals where it serves as a precursor for the synthesis of active pharmaceutical ingredients. It is also used in the production of dyes, pigments, and as a chemical intermediate in the synthesis of other organic compounds.

What precautions should be taken when handling 4-Amino-2-Methylphenol (CAS: 2635-95-2)?

When handling 4-Amino-2-Methylphenol, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. It should be stored in a cool, dry, well-ventilated area away from strong acids and bases. In case of spill, avoid direct contact and clean up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.